TopFIND 4.0

P04053: DNA nucleotidylexotransferase

General Information

Protein names
- DNA nucleotidylexotransferase
- 2.7.7.31 {ECO:0000269|PubMed:11473582, ECO:0000269|PubMed:16371131, ECO:0000269|PubMed:8163485}
- Terminal addition enzyme
- Terminal deoxynucleotidyltransferase
- Terminal transferase {ECO:0000303|PubMed:11473582}
Gene names DNTT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P04053

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDPPRASHLS PRKKRPRQTG ALMASSPQDI KFQDLVVFIL EKKMGTTRRA FLMELARRKG 
        70         80         90        100        110        120 
FRVENELSDS VTHIVAENNS GSDVLEWLQA QKVQVSSQPE LLDVSWLIEC IRAGKPVEMT 
       130        140        150        160        170        180 
GKHQLVVRRD YSDSTNPGPP KTPPIAVQKI SQYACQRRTT LNNCNQIFTD AFDILAENCE 
       190        200        210        220        230        240 
FRENEDSCVT FMRAASVLKS LPFTIISMKD TEGIPCLGSK VKGIIEEIIE DGESSEVKAV 
       250        260        270        280        290        300 
LNDERYQSFK LFTSVFGVGL KTSEKWFRMG FRTLSKVRSD KSLKFTRMQK AGFLYYEDLV 
       310        320        330        340        350        360 
SCVTRAEAEA VSVLVKEAVW AFLPDAFVTM TGGFRRGKKM GHDVDFLITS PGSTEDEEQL 
       370        380        390        400        410        420 
LQKVMNLWEK KGLLLYYDLV ESTFEKLRLP SRKVDALDHF QKCFLIFKLP RQRVDSDQSS 
       430        440        450        460        470        480 
WQEGKTWKAI RVDLVLCPYE RRAFALLGWT GSRQFERDLR RYATHERKMI LDNHALYDKT 
       490        500    
KRIFLKAESE EEIFAHLGLD YIEPWERNA

Isoforms

- Isoform 2 of DNA nucleotidylexotransferase

Sequence View

        10         20         30         40         50         60 
MDPPRASHLS PRKKRPRQTG ALMASSPQDI KFQDLVVFIL EKKMGTTRRA FLMELARRKG 
        70         80         90        100        110        120 
FRVENELSDS VTHIVAENNS GSDVLEWLQA QKVQVSSQPE LLDVSWLIEC IRAGKPVEMT 
       130        140        150        160        170        180 
GKHQLVVRRD YSDSTNPGPP KTPPIAVQKI SQYACQRRTT LNNCNQIFTD AFDILAENCE 
       190        200        210        220        230        240 
FRENEDSCVT FMRAASVLKS LPFTIISMKD TEGIPCLGSK VKGIIEEIIE DGESSEVKAV 
       250        260        270        280        290        300 
LNDERYQSFK LFTSVFGVGL KTSEKWFRMG FRTLSKVRSD KSLKFTRMQK AGFLYYEDLV 
       310        320        330        340        350        360 
SCVTRAEAEA VSVLVKEAVW AFLPDAFVTM TGGFRRGKKM GHDVDFLITS PGSTEDEEQL 
       370        380        390        400        410        420 
LQKVMNLWEK KGLLLYYDLV ESTFEKLRLP SRKVDALDHF QKCFLIFKLP RQRVDSDQSS 
       430        440        450        460        470        480 
WQEGKTWKAI RVDLVLCPYE RRAFALLGWT GSRQFERDLR RYATHERKMI LDNHALYDKT 
       490        500    
KRIFLKAESE EEIFAHLGLD YIEPWERNA



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P04053-1-unknown MDPPRA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P04053-1-unknown MDPPRA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91799

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...WERNA 509 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...WERNA 509 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87417

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)