TopFIND 4.0

P04798: Cytochrome P450 1A1 {ECO:0000303|PubMed:11555828}

General Information

Protein names
- Cytochrome P450 1A1 {ECO:0000303|PubMed:11555828}
- CYPIA1 {ECO:0000303|PubMed:10681376}
- 1.14.14.-
- Cytochrome P450 form 6
- Cytochrome P450-C
- Cytochrome P450-P1
- Hydroperoxy icosatetraenoate dehydratase {ECO:0000305|PubMed:21068195}
- 4.2.1.152 {ECO:0000269|PubMed:21068195}
Gene names CYP1A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P04798

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH 
        70         80         90        100        110        120 
LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS 
       130        140        150        160        170        180 
MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG 
       190        200        210        220        230        240 
PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL 
       250        260        270        280        290        300 
RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV 
       310        320        330        340        350        360 
QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS 
       370        380        390        400        410        420 
DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL 
       430        440        450        460        470        480 
WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF 
       490        500        510    
SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS

Isoforms

- Isoform 2 of Cytochrome P450 1A1 - Isoform 3 of Cytochrome P450 1A1

Sequence View

        10         20         30         40         50         60 
MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH 
        70         80         90        100        110        120 
LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS 
       130        140        150        160        170        180 
MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG 
       190        200        210        220        230        240 
PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL 
       250        260        270        280        290        300 
RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV 
       310        320        330        340        350        360 
QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS 
       370        380        390        400        410        420 
DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL 
       430        440        450        460        470        480 
WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF 
       490        500        510    
SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS         10         20         30         40         50         60 
MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH 
        70         80         90        100        110        120 
LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS 
       130        140        150        160        170        180 
MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG 
       190        200        210        220        230        240 
PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL 
       250        260        270        280        290        300 
RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV 
       310        320        330        340        350        360 
QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS 
       370        380        390        400        410        420 
DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL 
       430        440        450        460        470        480 
WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF 
       490        500        510    
SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P04798-1-unknown MLFPIS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P04798-1-unknown MLFPIS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71505
    P04798-262-unknown MQKMVK... 262 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71506

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...INHDQK 418 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt67124
    ...MQLRS 512 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)