TopFIND 4.0

P05093: Steroid 17-alpha-hydroxylase/17,20 lyase

General Information

Protein names
- Steroid 17-alpha-hydroxylase/17,20 lyase
- 1.14.14.19 {ECO:0000269|PubMed:22266943}
- 17-alpha-hydroxyprogesterone aldolase
- 1.14.14.32 {ECO:0000269|PubMed:22266943}
- CYPXVII
- Cytochrome P450 17A1
- Cytochrome P450-C17
- Cytochrome P450c17
- Steroid 17-alpha-monooxygenase
Gene names CYP17A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P05093

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MWELVALLLL TLAYLFWPKR RCPGAKYPKS LLSLPLVGSL PFLPRHGHMH NNFFKLQKKY 
        70         80         90        100        110        120 
GPIYSVRMGT KTTVIVGHHQ LAKEVLIKKG KDFSGRPQMA TLDIASNNRK GIAFADSGAH 
       130        140        150        160        170        180 
WQLHRRLAMA TFALFKDGDQ KLEKIICQEI STLCDMLATH NGQSIDISFP VFVAVTNVIS 
       190        200        210        220        230        240 
LICFNTSYKN GDPELNVIQN YNEGIIDNLS KDSLVDLVPW LKIFPNKTLE KLKSHVKIRN 
       250        260        270        280        290        300 
DLLNKILENY KEKFRSDSIT NMLDTLMQAK MNSDNGNAGP DQDSELLSDN HILTTIGDIF 
       310        320        330        340        350        360 
GAGVETTTSV VKWTLAFLLH NPQVKKKLYE EIDQNVGFSR TPTISDRNRL LLLEATIREV 
       370        380        390        400        410        420 
LRLRPVAPML IPHKANVDSS IGEFAVDKGT EVIINLWALH HNEKEWHQPD QFMPERFLNP 
       430        440        450        460        470        480 
AGTQLISPSV SYLPFGAGPR SCIGEILARQ ELFLIMAWLL QRFDLEVPDD GQLPSLEGIP 
       490        500    
KVVFLIDSFK VKIKVRQAWR EAQAEGST

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P05093-1-unknown MWELVA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AEGST 508 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)