P05187: Alkaline phosphatase, placental type
| Protein names | - Alkaline phosphatase, placental type - 3.1.3.1 - Alkaline phosphatase Regan isozyme - Placental alkaline phosphatase 1 - PLAP-1 |
|---|---|
| Gene names | ALPP |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P05187 |
2
N-termini
1
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLGPCMLLLL LLLGLRLQLS LGIIPVEEEN PDFWNREAAE ALGAAKKLQP AQTAAKNLII
70 80 90 100 110 120
FLGDGMGVST VTAARILKGQ KKDKLGPEIP LAMDRFPYVA LSKTYNVDKH VPDSGATATA
130 140 150 160 170 180
YLCGVKGNFQ TIGLSAAARF NQCNTTRGNE VISVMNRAKK AGKSVGVVTT TRVQHASPAG
190 200 210 220 230 240
TYAHTVNRNW YSDADVPASA RQEGCQDIAT QLISNMDIDV ILGGGRKYMF RMGTPDPEYP
250 260 270 280 290 300
DDYSQGGTRL DGKNLVQEWL AKRQGARYVW NRTELMQASL DPSVTHLMGL FEPGDMKYEI
310 320 330 340 350 360
HRDSTLDPSL MEMTEAALRL LSRNPRGFFL FVEGGRIDHG HHESRAYRAL TETIMFDDAI
370 380 390 400 410 420
ERAGQLTSEE DTLSLVTADH SHVFSFGGYP LRGSSIFGLA PGKARDRKAY TVLLYGNGPG
430 440 450 460 470 480
YVLKDGARPD VTESESGSPE YRQQSAVPLD EETHAGEDVA VFARGPQAHL VHGVQEQTFI
490 500 510 520 530
AHVMAFAACL EPYTACDLAP PAGTTDAAHP GRSVVPALLP LLAGTLLLLE TATAP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P05187-23-unknown | IIPVEE... | 23 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P05187-507-unknown | AAHPGR... | 507 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9861 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...AGTTDA | 506 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...AGTTDA | 506 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9861 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| GPI8_HUMAN | 506 | TTDA.|.AAHP | inferred from experiment | unknown | MEROPS | Harris H | Henthorn PS et al.:Products of two common alleles ... (C13.005) | 3461452, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|