P05231: Interleukin-6

General Information

Protein names	- Interleukin-6 - IL-6 - B-cell stimulatory factor 2 - BSF-2 - CTL differentiation factor - CDF - Hybridoma growth factor - Interferon beta-2 - IFN-beta-2
Gene names	IL6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P05231

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNSFSTSAFG PVAFSLGLLL VLPAAFPAPV PPGEDSKDVA APHRQPLTSS ERIDKQIRYI
        70         80         90        100        110        120
LDGISALRKE TCNKSNMCES SKEALAENNL NLPKMAEKDG CFQSGFNEET CLVKIITGLL
       130        140        150        160        170        180
EFEVYLEYLQ NRFESSEEQA RAVQMSTKVL IQFLQKKAKN LDAITTPDPT TNASLLTKLQ
       190        200        210
AQNQWLQDMT THLILRSFKE FLQSSLRALR QM

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P05231-30-unknown	VPPGED...	30	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P05231-77-unknown	MCESSK...	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000385718
P05231-77-unknown	MCESSK...	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000385043

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KVLIQF	152	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000405150
	...ALRQM	212	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)