TopFIND 4.0

P06169: Pyruvate decarboxylase isozyme 1

General Information

Protein names
- Pyruvate decarboxylase isozyme 1
- 4.1.1.- {ECO:0000269|PubMed:23642236, ECO:0000269|PubMed:4687392}
- 4.1.1.43 {ECO:0000269|PubMed:12499363}
- 4.1.1.72 {ECO:0000269|PubMed:10753893, ECO:0000269|PubMed:9748245}
- 4.1.1.74 {ECO:0000269|PubMed:12499363}
- Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase
- 2ODC
Gene names PDC1
Organism Saccharomyces cerevisiae
Protease Family
Protease ID
Chromosome location
UniProt ID P06169

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSEITLGKYL FERLKQVNVN TVFGLPGDFN LSLLDKIYEV EGMRWAGNAN ELNAAYAADG 
        70         80         90        100        110        120 
YARIKGMSCI ITTFGVGELS ALNGIAGSYA EHVGVLHVVG VPSISAQAKQ LLLHHTLGNG 
       130        140        150        160        170        180 
DFTVFHRMSA NISETTAMIT DIATAPAEID RCIRTTYVTQ RPVYLGLPAN LVDLNVPAKL 
       190        200        210        220        230        240 
LQTPIDMSLK PNDAESEKEV IDTILALVKD AKNPVILADA CCSRHDVKAE TKKLIDLTQF 
       250        260        270        280        290        300 
PAFVTPMGKG SIDEQHPRYG GVYVGTLSKP EVKEAVESAD LILSVGALLS DFNTGSFSYS 
       310        320        330        340        350        360 
YKTKNIVEFH SDHMKIRNAT FPGVQMKFVL QKLLTTIADA AKGYKPVAVP ARTPANAAVP 
       370        380        390        400        410        420 
ASTPLKQEWM WNQLGNFLQE GDVVIAETGT SAFGINQTTF PNNTYGISQV LWGSIGFTTG 
       430        440        450        460        470        480 
ATLGAAFAAE EIDPKKRVIL FIGDGSLQLT VQEISTMIRW GLKPYLFVLN NDGYTIEKLI 
       490        500        510        520        530        540 
HGPKAQYNEI QGWDHLSLLP TFGAKDYETH RVATTGEWDK LTQDKSFNDN SKIRMIEIML 
       550        560    
PVFDAPQNLV EQAKLTAATN AKQ

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P06169-2-unknown MSEITL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P06169-2-Acetylation SEITLG... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TNAKQ 563 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)