P06858: Lipoprotein lipase

General Information

Protein names	- Lipoprotein lipase - LPL - 3.1.1.34 {ECO:0000269\|PubMed:11342582, ECO:0000269\|PubMed:1371284, ECO:0000269\|PubMed:2340307, ECO:0000269\|PubMed:27578112, ECO:0000269\|PubMed:30559189}
Gene names	LPL
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P06858

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MESKALLVLT LAVWLQSLTA SRGGVAAADQ RRDFIDIESK FALRTPEDTA EDTCHLIPGV
        70         80         90        100        110        120
AESVATCHFN HSSKTFMVIH GWTVTGMYES WVPKLVAALY KREPDSNVIV VDWLSRAQEH
       130        140        150        160        170        180
YPVSAGYTKL VGQDVARFIN WMEEEFNYPL DNVHLLGYSL GAHAAGIAGS LTNKKVNRIT
       190        200        210        220        230        240
GLDPAGPNFE YAEAPSRLSP DDADFVDVLH TFTRGSPGRS IGIQKPVGHV DIYPNGGTFQ
       250        260        270        280        290        300
PGCNIGEAIR VIAERGLGDV DQLVKCSHER SIHLFIDSLL NEENPSKAYR CSSKEAFEKG
       310        320        330        340        350        360
LCLSCRKNRC NNLGYEINKV RAKRSSKMYL KTRSQMPYKV FHYQVKIHFS GTESETHTNQ
       370        380        390        400        410        420
AFEISLYGTV AESENIPFTL PEVSTNKTYS FLIYTEVDIG ELLMLKLKWK SDSYFSWSDW
       430        440        450        460        470
WSSPGFAIQK IRVKAGETQK KVIFCSREKV SHLQKGKAPA VFVKCHDKSL NKKSG

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P06858-28-unknown	ADQRRD...	28		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P06858-77-unknown	MVIHGW...	77		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000428496

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KREPDS	105	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428557
...AGYTKL	129	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428237
...PNFEYA	191	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428496
...NKKSG	475	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)