TopFIND 4.0

P07141: Macrophage colony-stimulating factor 1

General Information

Protein names
- Macrophage colony-stimulating factor 1
- CSF-1
- MCSF
- Processed macrophage colony-stimulating factor 1
Gene names Csf1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P07141

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTARGAAGRC PSSTWLGSRL LLVCLLMSRS IAKEVSEHCS HMIGNGHLKV LQQLIDSQME 
        70         80         90        100        110        120 
TSCQIAFEFV DQEQLDDPVC YLKKAFFLVQ DIIDETMRFK DNTPNANATE RLQELSNNLN 
       130        140        150        160        170        180 
SCFTKDYEEQ NKACVRTFHE TPLQLLEKIK NFFNETKNLL EKDWNIFTKN CNNSFAKCSS 
       190        200        210        220        230        240 
RDVVTKPDCN CLYPKATPSS DPASASPHQP PAPSMAPLAG LAWDDSQRTE GSSLLPSELP 
       250        260        270        280        290        300 
LRIEDPGSAK QRPPRSTCQT LESTEQPNHG DRLTEDSQPH PSAGGPVPGV EDILESSLGT 
       310        320        330        340        350        360 
NWVLEEASGE ASEGFLTQEA KFSPSTPVGG SIQAETDRPR ALSASPFPKS TEDQKPVDIT 
       370        380        390        400        410        420 
DRPLTEVNPM RPIGQTQNNT PEKTDGTSTL REDHQEPGSP HIATPNPQRV SNSATPVAQL 
       430        440        450        460        470        480 
LLPKSHSWGI VLPLGELEGK RSTRDRRSPA ELEGGSASEG AARPVARFNS IPLTDTGHVE 
       490        500        510        520        530        540 
QHEGSSDPQI PESVFHLLVP GIILVLLTVG GLLFYKWKWR SHRDPQTLDS SVGRPEDSSL 
       550    
TQDEDRQVEL PV

Isoforms

- Isoform 2 of Macrophage colony-stimulating factor 1

Sequence View

        10         20         30         40         50         60 
MTARGAAGRC PSSTWLGSRL LLVCLLMSRS IAKEVSEHCS HMIGNGHLKV LQQLIDSQME 
        70         80         90        100        110        120 
TSCQIAFEFV DQEQLDDPVC YLKKAFFLVQ DIIDETMRFK DNTPNANATE RLQELSNNLN 
       130        140        150        160        170        180 
SCFTKDYEEQ NKACVRTFHE TPLQLLEKIK NFFNETKNLL EKDWNIFTKN CNNSFAKCSS 
       190        200        210        220        230        240 
RDVVTKPDCN CLYPKATPSS DPASASPHQP PAPSMAPLAG LAWDDSQRTE GSSLLPSELP 
       250        260        270        280        290        300 
LRIEDPGSAK QRPPRSTCQT LESTEQPNHG DRLTEDSQPH PSAGGPVPGV EDILESSLGT 
       310        320        330        340        350        360 
NWVLEEASGE ASEGFLTQEA KFSPSTPVGG SIQAETDRPR ALSASPFPKS TEDQKPVDIT 
       370        380        390        400        410        420 
DRPLTEVNPM RPIGQTQNNT PEKTDGTSTL REDHQEPGSP HIATPNPQRV SNSATPVAQL 
       430        440        450        460        470        480 
LLPKSHSWGI VLPLGELEGK RSTRDRRSPA ELEGGSASEG AARPVARFNS IPLTDTGHVE 
       490        500        510        520        530        540 
QHEGSSDPQI PESVFHLLVP GIILVLLTVG GLLFYKWKWR SHRDPQTLDS SVGRPEDSSL 
       550    
TQDEDRQVEL PV



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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P07141-1-unknown MTARGA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71853
    P07141-33-unknown KEVSEH... 33 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P07141-33-unknown KEVSEH... 33 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt115073

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)