P07359: Platelet glycoprotein Ib alpha chain
| Protein names | - Platelet glycoprotein Ib alpha chain - GP-Ib alpha - GPIb-alpha - GPIbA - Glycoprotein Ibalpha - Antigen CD42b-alpha - CD42b - Glycocalicin |
|---|---|
| Gene names | GP1BA |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P07359 |
4
N-termini
5
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPLLLLLLLL PSPLHPHPIC EVSKVASHLE VNCDKRNLTA LPPDLPKDTT ILHLSENLLY
70 80 90 100 110 120
TFSLATLMPY TRLTQLNLDR CELTKLQVDG TLPVLGTLDL SHNQLQSLPL LGQTLPALTV
130 140 150 160 170 180
LDVSFNRLTS LPLGALRGLG ELQELYLKGN ELKTLPPGLL TPTPKLEKLS LANNNLTELP
190 200 210 220 230 240
AGLLNGLENL DTLLLQENSL YTIPKGFFGS HLLPFAFLHG NPWLCNCEIL YFRRWLQDNA
250 260 270 280 290 300
ENVYVWKQGV DVKAMTSNVA SVQCDNSDKF PVYKYPGKGC PTLGDEGDTD LYDYYPEEDT
310 320 330 340 350 360
EGDKVRATRT VVKFPTKAHT TPWGLFYSWS TASLDSQMPS SLHPTQESTK EQTTFPPRWT
370 380 390 400 410 420
PNFTLHMESI TFSKTPKSTT EPTPSPTTSE PVPEPAPNMT TLEPTPSPTT PEPTSEPAPS
430 440 450 460 470 480
PTTPEPTSEP APSPTTPEPT SEPAPSPTTP EPTPIPTIAT SPTILVSATS LITPKSTFLT
490 500 510 520 530 540
TTKPVSLLES TKKTIPELDQ PPKLRGVLQG HLESSRNDPF LHPDFCCLLP LGFYVLGLFW
550 560 570 580 590 600
LLFASVVLIL LLSWVGHVKP QALDSGQGAA LTTATQTTHL ELQRGRQVTV PRAWLLFLRG
610 620 630 640 650
SLPTFRSSLF LWVRPNGRVG PLVAGRRPSA LSQGRGQDLL STVSIRYSGH SL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P07359-17-unknown | HPICEV... | 17 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P07359-292-unknown | YDYYPE... | 292 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4777 | |||
| P07359-293-unknown | DYYPEE... | 293 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4778 | |||
| P07359-313-unknown | KFPTKA... | 313 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4779 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GDTDLY | 291 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4777 | |||
| ...DTDLYD | 292 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4778 | |||
| ...TRTVVK | 312 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4779 | |||
| ...SGHSL | 652 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CATG_HUMAN | 291 | TDLY.|.YDYY | inferred from experiment | unknown | MEROPS | Chignard M | Pidard D et al.:Neutrophil proteinase cathepsin... (S01.133) | 7980408, |
| CATG_HUMAN | 292 | DLYD.|.DYYP | inferred from experiment | unknown | MEROPS | Berndt MC | Gardiner EE et al.:Regulation of P-selectin bindin... (S01.133) | 11520793, |
| CATG_HUMAN | 312 | TVVK.|.KFPT | inferred from experiment | unknown | MEROPS | Chignard M | Pidard D et al.:Neutrophil proteinase cathepsin... (S01.133) | 7980408, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|