TopFIND 4.0

P08649: Complement C4

General Information

Protein names
- Complement C4
- Complement C4 beta chain
- Complement C4 alpha chain
- C4a anaphylatoxin
- Complement C4 gamma chain
Gene names C4
Organism Rattus norvegicus
Protease Family
Protease ID I39.951
Chromosome location
UniProt ID P08649

3

N-termini

4

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLLWGLAWA FSFFASSLQK PRLLLFSPSV VNLGTPLSVG VQLLDAPAGQ EVKGSVYLRN 
        70         80         90        100        110        120 
PTSGPCSPKK DFKLSSGNDF VLLRLEVPLK DVRSCGLFGL RRAPHIQLVA HSPWLKNTAS 
       130        140        150        160        170        180 
KATETQGVNL LFSSRRGHIF VQTDQPIYNP GQRVRYRVFA LDQKMRPSTD TLTVTVENSH 
       190        200        210        220        230        240 
GLRVRKKEVF APTSIFQDDF IIPDISEPGT WKISARFSDG LESNRSTHFE VKKYVLPNFE 
       250        260        270        280        290        300 
VKLTPWKPYI LTVPSYREEI QLDVQARYVY GKPVQGVAYT RFALMDEQGK KSFLRGLETQ 
       310        320        330        340        350        360 
TKLVEGQTHI SISRDQFQAA LGKVNTEIGD LEGLRLYAAV AVIESPGGEM EEAELTSWPF 
       370        380        390        400        410        420 
VSSAFSLDLS HTKQHLVPGA PFLLQALVRE MSGSEASDVP VKVSATLLSG SDSKVLDFQQ 
       430        440        450        460        470        480 
NTNGIGQVSF SIHVPPTITE LRLLVSAGSL YPAVAKLTVQ APPSRGPGFL SIEPLDLRSP 
       490        500        510        520        530        540 
RVGDTFVLSL RTVGIPMPTF SHYYYMIISR GQIMAMSREP RRALTSISVL VDHHLAPSFY 
       550        560        570        580        590        600 
FVAYFYHQGL PVANSLLINV QPGDCEGKLE LKVDGAKEYR NGDSMKLQLQ TDSEALVALG 
       610        620        630        640        650        660 
AVDTALYAVG GRSHKPLDMS KVFEVMNSYN LGCGPGGGDD ALQVFQTAGL AFSDGDRLTQ 
       670        680        690        700        710        720 
TKENLSCPKE KKSRQKRNVN FQKAISEKLG QYSSPDTKRC CQDGMTKLPM ARTCEQRAAR 
       730        740        750        760        770        780 
VPQPACREPF LSCCKFAEDL RRNQTRSQAG LARAQDMLQE EDLIDEDDIL VRSFFPENWL 
       790        800        810        820        830        840 
WRVEPVDRSK LLTVWLPDSL TTWEIHGVSL SKSKGLCVAK PTRVRVFREF HLHLRLPISV 
       850        860        870        880        890        900 
RRFEQLELRP VLYNYLSEDV TVSVHVSPVE GLCLAGGGLL AQQVSVPAGS ARPVAFSVVP 
       910        920        930        940        950        960 
TAAASIPLKV VARGSFTIGD AVSKILQIEK EGAIHREEIV YNLDPLNNLG RSLEIPGSSD 
       970        980        990       1000       1010       1020 
PNVIPDGDFS SFVRVTASEP LETLGSEGAL SPGGVASLLR LPRGCAEQTM IYLAPTLTAS 
      1030       1040       1050       1060       1070       1080 
HYLDRTEQWS KLPPETKDHA VDLIQKGHMR IQQFRKKDGS FGAWLHRDSS TWLTAFVLKI 
      1090       1100       1110       1120       1130       1140 
LSLAQEQIGD SPEKLQETAG WLLGQQLDDG SFHDPCPVIH RGMQGGLVGT DETVALTAFV 
      1150       1160       1170       1180       1190       1200 
VIALHHGLAV FQDENSQQLK KRVEASITKA NSFLGQKASA GLLGAHASAI TAYALTLTKA 
      1210       1220       1230       1240       1250       1260 
SEDLQNVAHN SLMAMAEETG ENLYWGSAIG SQDNVVSSTP APRNPSEPVP QAPALWIETT 
      1270       1280       1290       1300       1310       1320 
AYGLLHLLLR EGKGEMADKV ATWLTHQGSF QGGFRSTQDT VVTLDALSAY WIASHTTEEK 
      1330       1340       1350       1360       1370       1380 
ALNVTLSSMG RNGYKSHLLQ LNNHQVKGLE EELKFSLGST INVKVGGNSK GTLKILRTYN 
      1390       1400       1410       1420       1430       1440 
VLDMKNTTCQ DLRIEVTVTG YVEYTREANE DYEYDYDMPA ADDPSVHSQP VTPLQLFEGR 
      1450       1460       1470       1480       1490       1500 
RSRRRREAPK AADEQESRVQ YTVCIWRNGN LGLSGMAIAD ITLLSGFQAL RADLEKLTSL 
      1510       1520       1530       1540       1550       1560 
SDRYVSHFET DGPHVLLYFD SVPTTRECVG FGALQEVAVG LVQPASAVLY DYYSPDHKCS 
      1570       1580       1590       1600       1610       1620 
VFYAAPTKSK LLSTLCSADV CQCAEGKCPR QRRSLERGVE DKDGYRMKFA CYYPRVEYGF 
      1630       1640       1650       1660       1670       1680 
QVKVLREDSR AAFRLFETKI TQVLHFTKDA KASIGQTRNF LVRASCRLRL EPSKEYLIMG 
      1690       1700       1710       1720       1730    
MDGVTSDLKG DPQYLLDSNT WIEEMPSERL CRSTRQRAAC GQLNDFLQEY SSQGCQV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P08649-20-unknown KPRLLL... 20 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P08649-678-unknown NVNFQK... 678 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P08649-1447-unknown EAPKAA... 1447 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)