P08910: Monoacylglycerol lipase ABHD2 {ECO:0000305}

General Information

Protein names	- Monoacylglycerol lipase ABHD2 {ECO:0000305} - 3.1.1.23 {ECO:0000269\|PubMed:26989199} - 2-arachidonoylglycerol hydrolase {ECO:0000305} - Abhydrolase domain-containing protein 2 {ECO:0000305} - Acetylesterase {ECO:0000305} - 3.1.1.6 {ECO:0000269\|PubMed:27247428} - Lung alpha/beta hydrolase 2 {ECO:0000250\|UniProtKB:Q9QXM0} - Progesterone-sensitive lipase {ECO:0000305} - 3.1.1.79 {ECO:0000269\|PubMed:27247428} - Protein PHPS1-2 {ECO:0000303\|PubMed:2843827}
Gene names	ABHD2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P08910

1 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNAMLETPEL PAVFDGVKLA AVAAVLYVIV RCLNLKSPTA PPDLYFQDSG LSRFLLKSCP
        70         80         90        100        110        120
LLTKEYIPPL IWGKSGHIQT ALYGKMGRVR SPHPYGHRKF ITMSDGATST FDLFEPLAEH
       130        140        150        160        170        180
CVGDDITMVI CPGIANHSEK QYIRTFVDYA QKNGYRCAVL NHLGALPNIE LTSPRMFTYG
       190        200        210        220        230        240
CTWEFGAMVN YIKKTYPLTQ LVVVGFSLGG NIVCKYLGET QANQEKVLCC VSVCQGYSAL
       250        260        270        280        290        300
RAQETFMQWD QCRRFYNFLM ADNMKKIILS HRQALFGDHV KKPQSLEDTD LSRLYTATSL
       310        320        330        340        350        360
MQIDDNVMRK FHGYNSLKEY YEEESCMRYL HRIYVPLMLV NAADDPLVHE SLLTIPKSLS
       370        380        390        400        410        420
EKRENVMFVL PLHGGHLGFF EGSVLFPEPL TWMDKLVVEY ANAICQWERN KLQCSDTEQV

EADLE

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

1 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P08910-1-unknown	MNAMLE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LSRFLL	55	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454645
...EHCVGD	123	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454531
...TMVICP	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457882
...EADLE	425	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)