TopFIND 4.0

P08934: Kininogen-1

General Information

Protein names
- Kininogen-1
- Kininogen-1 heavy chain
- Bradykinin
- Kininogen-1 light chain
Gene names Kng1
Organism Rattus norvegicus
Protease Family
Protease ID I25.018
Chromosome location
UniProt ID P08934

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLITILLLC SRLLPSLAQE EDAQEMDCND ESLFQAVDTA LKKYNAGLKS GNQFVLYQVT 
        70         80         90        100        110        120 
EGTKKDGSKT FYSFKYQIKE GNCSVQSGFA WQDCDFKDAE EAATGECTAT LEKRRNNKFS 
       130        140        150        160        170        180 
IATQICNITP GKGPIVTNEY HCLGCMHPIS VDSPELGPVL KHAVEHFNNN TKHTHLFALG 
       190        200        210        220        230        240 
EVKSADRQVV AGMNYQIIYS IVQTNCSKED FPSLHEDCVP LPSGDDGECK GNAFVDIHKT 
       250        260        270        280        290        300 
IAGFSDSCEF YPGDDLFELL PEDCPGCPRN IPVDSPELKE ALGHSIAQLN AENNHTFYFK 
       310        320        330        340        350        360 
IDTVKKATSQ VVAGTKYVIE FIARETKCSK ESNAELTADC ETKRLGQSLN CNANVYMRPW 
       370        380        390        400        410        420 
ENKVVPTVKC KVLDMTSVIR RPPGFSPFRA PRVKKPKEST TVSPSYIARV QEERDPGNEQ 
       430        440        450        460        470        480 
GPIHGHGWLH AKQIKNKNHQ GHKHGHGIGH GHQKPHGLGH GHQLKLDDLK QQREDGYDHR 
       490        500        510        520        530        540 
HPVGHGHGQR HGHGHGHGHG RDKHTNKDKN NVKHTDQRRA PLTSSSEDNT TSTQIQGRTE 
       550        560        570        580        590        600 
GFTLNPPLAQ PAVISRGFQD SGFTEGVIAT TSPYDTETHD DLIPDIHVQP DSLSFKLISD 
       610        620        630    
FPEATSHKCP GRPWKPVSRK DPTIETTEFS DFDLLDALS

Isoforms

- Isoform LMW of Kininogen-1

Sequence View

        10         20         30         40         50         60 
MKLITILLLC SRLLPSLAQE EDAQEMDCND ESLFQAVDTA LKKYNAGLKS GNQFVLYQVT 
        70         80         90        100        110        120 
EGTKKDGSKT FYSFKYQIKE GNCSVQSGFA WQDCDFKDAE EAATGECTAT LEKRRNNKFS 
       130        140        150        160        170        180 
IATQICNITP GKGPIVTNEY HCLGCMHPIS VDSPELGPVL KHAVEHFNNN TKHTHLFALG 
       190        200        210        220        230        240 
EVKSADRQVV AGMNYQIIYS IVQTNCSKED FPSLHEDCVP LPSGDDGECK GNAFVDIHKT 
       250        260        270        280        290        300 
IAGFSDSCEF YPGDDLFELL PEDCPGCPRN IPVDSPELKE ALGHSIAQLN AENNHTFYFK 
       310        320        330        340        350        360 
IDTVKKATSQ VVAGTKYVIE FIARETKCSK ESNAELTADC ETKRLGQSLN CNANVYMRPW 
       370        380        390        400        410        420 
ENKVVPTVKC KVLDMTSVIR RPPGFSPFRA PRVKKPKEST TVSPSYIARV QEERDPGNEQ 
       430        440        450        460        470        480 
GPIHGHGWLH AKQIKNKNHQ GHKHGHGIGH GHQKPHGLGH GHQLKLDDLK QQREDGYDHR 
       490        500        510        520        530        540 
HPVGHGHGQR HGHGHGHGHG RDKHTNKDKN NVKHTDQRRA PLTSSSEDNT TSTQIQGRTE 
       550        560        570        580        590        600 
GFTLNPPLAQ PAVISRGFQD SGFTEGVIAT TSPYDTETHD DLIPDIHVQP DSLSFKLISD 
       610        620        630    
FPEATSHKCP GRPWKPVSRK DPTIETTEFS DFDLLDALS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TSVIRR 380 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LDALS 639 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)