P09012: U1 small nuclear ribonucleoprotein A

General Information

Protein names	- U1 small nuclear ribonucleoprotein A - U1 snRNP A - U1-A - U1A
Gene names	SNRPA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09012

8 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVPETRPNH TIYINNLNEK IKKDELKKSL YAIFSQFGQI LDILVSRSLK MRGQAFVIFK
        70         80         90        100        110        120
EVSSATNALR SMQGFPFYDK PMRIQYAKTD SDIIAKMKGT FVERDRKREK RKPKSQETPA
       130        140        150        160        170        180
TKKAVQGGGA TPVVGAVQGP VPGMPPMTQA PRIMHHMPGQ PPYMPPPGMI PPPGLAPGQI
       190        200        210        220        230        240
PPGAMPPQQL MPGQMPPAQP LSENPPNHIL FLTNLPEETN ELMLSMLFNQ FPGFKEVRLV
       250        260        270        280
PGRHDIAFVE FDNEVQAGAA RDALQGFKIT QNNAMKISFA KK

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P09012-2-unknown	MAVPET...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09012-2-Acetylation	AVPETR...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09012-51-unknown	MRGQAF...	51		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470534
P09012-124-	AVQGGG...	124			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P09012-130-unknown	ATPVVG...	130			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P09012-130-	ATPVVG...	130			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P09012-130-	ATPVVG...	130			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P09012-130-	ATPVVG...	130			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P09012-130-	ATPVVG...	130			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P09012-130-	ATPVVG...	130			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P09012-136-unknown	AVQGPV...	136			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P09012-136-unknown	AVQGPV...	136			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P09012-136-	AVQGPV...	136			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P09012-136-	AVQGPV...	136			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P09012-136-	AVQGPV...	136			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P09012-136-	AVQGPV...	136			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P09012-136-	AVQGPV...	136			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGGATP	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469224
...QGPVPG	142	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472258
...MPPMTQ	148	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472449
...QFPGFK	234	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470534
...NAMKIS	277	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472355
...SFAKK	282	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)