P09093: Chymotrypsin-like elastase family member 3A

General Information

Protein names	- Chymotrypsin-like elastase family member 3A - 3.4.21.70 - Elastase IIIA - Elastase-3A - Protease E
Gene names	CELA3A
Organism	Homo sapiens
Protease Family
Protease ID	S01.154
Chromosome location
UniProt ID	P09093

2 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMLRLLSSLL LVAVASGYGP PSSHSSSRVV HGEDAVPYSW PWQVSLQYEK SGSFYHTCGG
        70         80         90        100        110        120
SLIAPDWVVT AGHCISRDLT YQVVLGEYNL AVKEGPEQVI PINSEELFVH PLWNRSCVAC
       130        140        150        160        170        180
GNDIALIKLS RSAQLGDAVQ LASLPPAGDI LPNKTPCYIT GWGRLYTNGP LPDKLQQARL
       190        200        210        220        230        240
PVVDYKHCSR WNWWGSTVKK TMVCAGGYIR SGCNGDSGGP LNCPTEDGGW QVHGVTSFVS
       250        260        270
AFGCNFIWKP TVFTRVSAFI DWIEETIASH

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P09093-29-unknown	VVHGED...	29	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P09093-29-unknown	VVHGED...	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16299
P09093-193-unknown	WWGSTV...	193	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000383130

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HSSSRV	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16299
...CVACGN	121	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000363795
...TIASH	270	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
KLK4_HUMAN	28	SSRV.\|.VVHG	inferred from experiment	unknown	MEROPS	Nelson PS	Matsumura M et al.:Substrates of the prostate-spec... (S01.251)	15389820,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)