TopFIND 4.0

P09151: 2-isopropylmalate synthase

General Information

Protein names
- 2-isopropylmalate synthase
- 2.3.3.13
- Alpha-IPM synthase
- Alpha-isopropylmalate synthase
Gene names leuA
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P09151

1

N-termini

1

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQQVIIFDT TLRDGEQALQ ASLSVKEKLQ IALALERMGV DVMEVGFPVS SPGDFESVQT 
        70         80         90        100        110        120 
IARQVKNSRV CALARCVEKD IDVAAESLKV AEAFRIHTFI ATSPMHIATK LRSTLDEVIE 
       130        140        150        160        170        180 
RAIYMVKRAR NYTDDVEFSC EDAGRTPIAD LARVVEAAIN AGATTINIPD TVGYTMPFEF 
       190        200        210        220        230        240 
AGIISGLYER VPNIDKAIIS VHTHDDLGLA VGNSLAAVHA GARQVEGAMN GIGERAGNCS 
       250        260        270        280        290        300 
LEEVIMAIKV RKDILNVHTA INHQEIWRTS QLVSQICNMP IPANKAIVGS GAFAHSSGIH 
       310        320        330        340        350        360 
QDGVLKNREN YEIMTPESIG LNQIQLNLTS RSGRAAVKHR MDEMGYKESE YNLDNLYDAF 
       370        380        390        400        410        420 
LKLADKKGQV FDYDLEALAF IGKQQEEPEH FRLDYFSVQS GSNDIATAAV KLACGEEVKA 
       430        440        450        460        470        480 
EAANGNGPVD AVYQAINRIT EYNVELVKYS LTAKGHGKDA LGQVDIVANY NGRRFHGVGL 
       490        500        510        520    
ATDIVESSAK AMVHVLNNIW RAAEVEKELQ RKAQHNENNK ETV

Isoforms



Sequence View



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P09151-2-unknown SQQVII... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P09151-2-unknown SQQVII... 2 inferred from cleavage unknown TopFIND Inferred from cleavage TC28052

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NKETV 523 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)