TopFIND 4.0

P0A6A6: 3-isopropylmalate dehydratase large subunit {ECO:0000255|HAMAP-Rule:MF_01026}

General Information

Protein names
- 3-isopropylmalate dehydratase large subunit {ECO:0000255|HAMAP-Rule:MF_01026}
- 4.2.1.33 {ECO:0000255|HAMAP-Rule:MF_01026}
- Alpha-IPM isomerase {ECO:0000255|HAMAP-Rule:MF_01026}
- IPMI {ECO:0000255|HAMAP-Rule:MF_01026}
- Isopropylmalate isomerase {ECO:0000255|HAMAP-Rule:MF_01026}
Gene names leuC
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P0A6A6

1

N-termini

1

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAKTLYEKLF DAHVVYEAEN ETPLLYIDRH LVHEVTSPQA FDGLRAHGRP VRQPGKTFAT 
        70         80         90        100        110        120 
MDHNVSTQTK DINACGEMAR IQMQELIKNC KEFGVELYDL NHPYQGIVHV MGPEQGVTLP 
       130        140        150        160        170        180 
GMTIVCGDSH TATHGAFGAL AFGIGTSEVE HVLATQTLKQ GRAKTMKIEV QGKAAPGITA 
       190        200        210        220        230        240 
KDIVLAIIGK TGSAGGTGHV VEFCGEAIRD LSMEGRMTLC NMAIEMGAKA GLVAPDETTF 
       250        260        270        280        290        300 
NYVKGRLHAP KGKDFDDAVA YWKTLQTDEG ATFDTVVTLQ AEEISPQVTW GTNPGQVISV 
       310        320        330        340        350        360 
NDNIPDPASF ADPVERASAE KALAYMGLKP GIPLTEVAID KVFIGSCTNS RIEDLRAAAE 
       370        380        390        400        410        420 
IAKGRKVAPG VQALVVPGSG PVKAQAEAEG LDKIFIEAGF EWRLPGCSMC LAMNNDRLNP 
       430        440        450        460    
GERCASTSNR NFEGRQGRGG RTHLVSPAMA AAAAVTGHFA DIRNIK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P0A6A6-2-unknown AKTLYE... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P0A6A6-2-unknown AKTLYE... 2 inferred from cleavage unknown TopFIND Inferred from cleavage TC28057

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IRNIK 466 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)