TopFIND 4.0

P0AAI3: ATP-dependent zinc metalloprotease FtsH {ECO:0000255|HAMAP-Rule:MF_01458}

General Information

Protein names
- ATP-dependent zinc metalloprotease FtsH {ECO:0000255|HAMAP-Rule:MF_01458}
- 3.4.24.- {ECO:0000255|HAMAP-Rule:MF_01458}
- Cell division protease FtsH
Gene names ftsH
Organism Escherichia coli
Protease Family M41.001
Protease ID M41.001
Chromosome location
UniProt ID P0AAI3

2

N-termini

2

C-termini

1

Cleavages

1

Substrates

Sequence

        10         20         30         40         50         60 
MAKNLILWLV IAVVLMSVFQ SFGPSESNGR KVDYSTFLQE VNNDQVREAR INGREINVTK 
        70         80         90        100        110        120 
KDSNRYTTYI PVQDPKLLDN LLTKNVKVVG EPPEEPSLLA SIFISWFPML LLIGVWIFFM 
       130        140        150        160        170        180 
RQMQGGGGKG AMSFGKSKAR MLTEDQIKTT FADVAGCDEA KEEVAELVEY LREPSRFQKL 
       190        200        210        220        230        240 
GGKIPKGVLM VGPPGTGKTL LAKAIAGEAK VPFFTISGSD FVEMFVGVGA SRVRDMFEQA 
       250        260        270        280        290        300 
KKAAPCIIFI DEIDAVGRQR GAGLGGGHDE REQTLNQMLV EMDGFEGNEG IIVIAATNRP 
       310        320        330        340        350        360 
DVLDPALLRP GRFDRQVVVG LPDVRGREQI LKVHMRRVPL APDIDAAIIA RGTPGFSGAD 
       370        380        390        400        410        420 
LANLVNEAAL FAARGNKRVV SMVEFEKAKD KIMMGAERRS MVMTEAQKES TAYHEAGHAI 
       430        440        450        460        470        480 
IGRLVPEHDP VHKVTIIPRG RALGVTFFLP EGDAISASRQ KLESQISTLY GGRLAEEIIY 
       490        500        510        520        530        540 
GPEHVSTGAS NDIKVATNLA RNMVTQWGFS EKLGPLLYAE EEGEVFLGRS VAKAKHMSDE 
       550        560        570        580        590        600 
TARIIDQEVK ALIERNYNRA RQLLTDNMDI LHAMKDALMK YETIDAPQID DLMARRDVRP 
       610        620        630        640    
PAGWEEPGAS NNSGDNGSPK APRPVDEPRT PNPGNTMSEQ LGDK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 1 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P0AAI3-1-unknown MAKNLI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P0AAI3-638-unknown SEQLGD... 638 inferred from cleavage unknown TopFIND Inferred from cleavage TC27818

C-termini

Cleavages

Substrates