TopFIND 4.0

P0ACD8: Hydrogenase-1 large chain

General Information

Protein names
- Hydrogenase-1 large chain
- HYD1
- 1.12.99.6
- Membrane-bound hydrogenase 1 large subunit
- NiFe hydrogenase
Gene names hyaB
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P0ACD8

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSTQYETQGY TINNAGRRLV VDPITRIEGH MRCEVNINDQ NVITNAVSCG TMFRGLEIIL 
        70         80         90        100        110        120 
QGRDPRDAWA FVERICGVCT GVHALASVYA IEDAIGIKVP DNANIIRNIM LATLWCHDHL 
       130        140        150        160        170        180 
VHFYQLAGMD WIDVLDALKA DPRKTSELAQ SLSSWPKSSP GYFFDVQNRL KKFVEGGQLG 
       190        200        210        220        230        240 
IFRNGYWGHP QYKLPPEANL MGFAHYLEAL DFQREIVKIH AVFGGKNPHP NWIVGGMPCA 
       250        260        270        280        290        300 
INIDESGAVG AVNMERLNLV QSIITRTADF INNVMIPDAL AIGQFNKPWS EIGTGLSDKC 
       310        320        330        340        350        360 
VLSYGAFPDI ANDFGEKSLL MPGGAVINGD FNNVLPVDLV DPQQVQEFVD HAWYRYPNDQ 
       370        380        390        400        410        420 
VGRHPFDGIT DPWYNPGDVK GSDTNIQQLN EQERYSWIKA PRWRGNAMEV GPLARTLIAY 
       430        440        450        460        470        480 
HKGDAATVES VDRMMSALNL PLSGIQSTLG RILCRAHEAQ WAAGKLQYFF DKLMTNLKNG 
       490        500        510        520        530        540 
NLATASTEKW EPATWPTECR GVGFTEAPRG ALGHWAAIRD GKIDLYQCVV PTTWNASPRD 
       550        560        570        580        590    
PKGQIGAYEA ALMNTKMAIP EQPLEILRTL HSFDPCLACS THVLGDDGSE LISVQVR

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P0ACD8-1-unknown MSTQYE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P0ACD8-583-unknown VLGDDG... 583 inferred from cleavage unknown TopFIND Inferred from cleavage TC27888

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)