P0ACE0: Hydrogenase-2 large chain
| Protein names | - Hydrogenase-2 large chain - HYD2 - 1.12.99.6 - Membrane-bound hydrogenase 2 large subunit - NiFe hydrogenase |
|---|---|
| Gene names | hybC |
| Organism | Escherichia coli |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P0ACE0 |
2
N-termini
1
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSQRITIDPV TRIEGHLRID CEIENGVVSK AWASGTMWRG MEEIVKNRDP RDAWMIVQRI
70 80 90 100 110 120
CGVCTTTHAL SSVRAAESAL NIDVPVNAQY IRNIILAAHT THDHIVHFYQ LSALDWVDIT
130 140 150 160 170 180
SALQADPTKA SEMLKGVSTW HLNSPEEFTK VQNKIKDLVA SGQLGIFANG YWGHPAMKLP
190 200 210 220 230 240
PEVNLIAVAH YLQALECQRD ANRVVALLGG KTPHIQNLAV GGVANPINLD GLGVLNLERL
250 260 270 280 290 300
MYIKSFIDKL SDFVEQVYKV DTAVIAAFYP EWLTRGKGAV NYLSVPEFPT DSKNGSFLFP
310 320 330 340 350 360
GGYIENADLS SYRPITSHSD EYLIKGIQES AKHSWYKDEA PQAPWEGTTI PAYDGWSDDG
370 380 390 400 410 420
KYSWVKSPTF YGKTVEVGPL ANMLVKLAAG RESTQNKLNE IVAIYQKLTG NTLEVAQLHS
430 440 450 460 470 480
TLGRIIGRTV HCCELQDILQ NQYSALITNI GKGDHTTFVK PNIPATGEFK GVGFLEAPRG
490 500 510 520 530 540
MLSHWMVIKD GIISNYQAVV PSTWNSGPRN FNDDVGPYEQ SLVGTPVADP NKPLEVVRTI
550 560
HSFDPCMACA VHVVDADGNE VVSVKVL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P0ACE0-2-unknown | SQRITI... | 2 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P0ACE0-2-unknown | SQRITI... | 2 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28175 | |||
| P0ACE0-553-unknown | VVDADG... | 553 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27889 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...ACAVHV | 552 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...ACAVHV | 552 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27889 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MAP1_ECOLI | 1 | .|.SQRI | inferred from experiment | unknown | MEROPS | Boxer DH | Sargent F et al.:Reassignment of the gene encodi... (S26.001) | 9738917, |
| HYBD_ECOLI | 552 | AVHV.|.VVDA | inferred from experiment | unknown | MEROPS | Bock A | Theodoratou E et al.:Analysis of the cleavage site s... (A31.001) | 10795682, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|