TopFIND 4.0

P0AD65: Peptidoglycan D,D-transpeptidase MrdA {ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000305}

General Information

Protein names
- Peptidoglycan D,D-transpeptidase MrdA {ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000305}
- 3.4.16.4 {ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000269|PubMed:3009484}
- Penicillin-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000303|PubMed:1103132, ECO:0000303|PubMed:3009484}
- PBP-2 {ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000303|PubMed:3009484}
Gene names mrdA
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P0AD65

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLQNSFRDY TAESALFVRR ALVAFLGILL LTGVLIANLY NLQIVRFTDY QTRSNENRIK 
        70         80         90        100        110        120 
LVPIAPSRGI IYDRNGIPLA LNRTIYQIEM MPEKVDNVQQ TLDALRSVVD LTDDDIAAFR 
       130        140        150        160        170        180 
KERARSHRFT SIPVKTNLTE VQVARFAVNQ YRFPGVEVKG YKRRYYPYGS ALTHVIGYVS 
       190        200        210        220        230        240 
KINDKDVERL NNDGKLANYA ATHDIGKLGI ERYYEDVLHG QTGYEEVEVN NRGRVIRQLK 
       250        260        270        280        290        300 
EVPPQAGHDI YLTLDLKLQQ YIETLLAGSR AAVVVTDPRT GGVLALVSTP SYDPNLFVDG 
       310        320        330        340        350        360 
ISSKDYSALL NDPNTPLVNR ATQGVYPPAS TVKPYVAVSA LSAGVITRNT TLFDPGWWQL 
       370        380        390        400        410        420 
PGSEKRYRDW KKWGHGRLNV TRSLEESADT FFYQVAYDMG IDRLSEWMGK FGYGHYTGID 
       430        440        450        460        470        480 
LAEERSGNMP TREWKQKRFK KPWYQGDTIP VGIGQGYWTA TPIQMSKALM ILINDGIVKV 
       490        500        510        520        530        540 
PHLLMSTAED GKQVPWVQPH EPPVGDIHSG YWELAKDGMY GVANRPNGTA HKYFASAPYK 
       550        560        570        580        590        600 
IAAKSGTAQV FGLKANETYN AHKIAERLRD HKLMTAFAPY NNPQVAVAMI LENGGAGPAV 
       610        620        630    
GTLMRQILDH IMLGDNNTDL PAENPAVAAA EDH

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P0AD65-1-unknown MKLQNS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AAEDH 633 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)