TopFIND 4.0

P0AD68: Peptidoglycan D,D-transpeptidase FtsI {ECO:0000255|HAMAP-Rule:MF_02080, ECO:0000305}

General Information

Protein names
- Peptidoglycan D,D-transpeptidase FtsI {ECO:0000255|HAMAP-Rule:MF_02080, ECO:0000305}
- 3.4.16.4 {ECO:0000255|HAMAP-Rule:MF_02080, ECO:0000269|PubMed:3531167, ECO:0000269|PubMed:6450748, ECO:0000269|PubMed:7030331}
- Essential cell division protein FtsI {ECO:0000305}
- Murein transpeptidase {ECO:0000303|PubMed:6450748}
- Penicillin-binding protein 3 {ECO:0000255|HAMAP-Rule:MF_02080, ECO:0000303|PubMed:1103132, ECO:0000303|PubMed:7030331}
- PBP-3 {ECO:0000255|HAMAP-Rule:MF_02080, ECO:0000303|PubMed:7030331}
- Peptidoglycan synthase FtsI {ECO:0000305}
Gene names ftsI
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P0AD68

2

N-termini

1

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKAAAKTQKP KRQEEHANFI SWRFALLCGC ILLALAFLLG RVAWLQVISP DMLVKEGDMR 
        70         80         90        100        110        120 
SLRVQQVSTS RGMITDRSGR PLAVSVPVKA IWADPKEVHD AGGISVGDRW KALANALNIP 
       130        140        150        160        170        180 
LDQLSARINA NPKGRFIYLA RQVNPDMADY IKKLKLPGIH LREESRRYYP SGEVTAHLIG 
       190        200        210        220        230        240 
FTNVDSQGIE GVEKSFDKWL TGQPGERIVR KDRYGRVIED ISSTDSQAAH NLALSIDERL 
       250        260        270        280        290        300 
QALVYRELNN AVAFNKAESG SAVLVDVNTG EVLAMANSPS YNPNNLSGTP KEAMRNRTIT 
       310        320        330        340        350        360 
DVFEPGSTVK PMVVMTALQR GVVRENSVLN TIPYRINGHE IKDVARYSEL TLTGVLQKSS 
       370        380        390        400        410        420 
NVGVSKLALA MPSSALVDTY SRFGLGKATN LGLVGERSGL YPQKQRWSDI ERATFSFGYG 
       430        440        450        460        470        480 
LMVTPLQLAR VYATIGSYGI YRPLSITKVD PPVPGERVFP ESIVRTVVHM MESVALPGGG 
       490        500        510        520        530        540 
GVKAAIKGYR IAIKTGTAKK VGPDGRYINK YIAYTAGVAP ASQPRFALVV VINDPQAGKY 
       550        560        570        580    
YGGAVSAPVF GAIMGGVLRT MNIEPDALTT GDKNEFVINQ GEGTGGRS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)