P0C0V0: Periplasmic serine endoprotease DegP
| Protein names | - Periplasmic serine endoprotease DegP - 3.4.21.107 {ECO:0000269|PubMed:8830688} - Heat shock protein DegP - Protease Do |
|---|---|
| Gene names | degP |
| Organism | Escherichia coli |
| Protease Family | S01.273 |
| Protease ID | S01.273 |
| Chromosome location | |
| UniProt ID | P0C0V0 |
3
N-termini
4
C-termini
3
Cleavages
2
Substrates
Sequence
10 20 30 40 50 60
MKKTTLALSA LALSLGLALS PLSATAAETS SATTAQQMPS LAPMLEKVMP SVVSINVEGS
70 80 90 100 110 120
TTVNTPRMPR NFQQFFGDDS PFCQEGSPFQ SSPFCQGGQG GNGGGQQQKF MALGSGVIID
130 140 150 160 170 180
ADKGYVVTNN HVVDNATVIK VQLSDGRKFD AKMVGKDPRS DIALIQIQNP KNLTAIKMAD
190 200 210 220 230 240
SDALRVGDYT VAIGNPFGLG ETVTSGIVSA LGRSGLNAEN YENFIQTDAA INRGNSGGAL
250 260 270 280 290 300
VNLNGELIGI NTAILAPDGG NIGIGFAIPS NMVKNLTSQM VEYGQVKRGE LGIMGTELNS
310 320 330 340 350 360
ELAKAMKVDA QRGAFVSQVL PNSSAAKAGI KAGDVITSLN GKPISSFAAL RAQVGTMPVG
370 380 390 400 410 420
SKLTLGLLRD GKQVNVNLEL QQSSQNQVDS SSIFNGIEGA EMSNKGKDQG VVVNNVKTGT
430 440 450 460 470
PAAQIGLKKG DVIIGANQQA VKNIAELRKV LDSKPSVLAL NIQRGDSTIY LLMQ
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 4 C-termini - 3 Cleavages - 2 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P0C0V0-27-unknown | AETSSA... | 27 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P0C0V0-27-unknown | AETSSA... | 27 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27949 | |||
| P0C0V0-96-unknown | QGGQGG... | 96 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27813 | |||
| P0C0V0-109-unknown | KFMALG... | 109 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27814 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LSATAA | 26 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27949 | |||
| ...SSPFCQ | 95 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27813 | |||
| ...GGQQQK | 108 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27814 | |||
| ...YLLMQ | 474 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| LEP_ECOLI | 26 | ATAA.|.AETS | inferred from experiment | unknown | MEROPS | Hochstrasser DF | Wilkins MR et al.:Protein identification with N a... (S26.001) | 9600841, |
| DEGP_ECOLI | 95 | PFCQ.|.QGGQ | inferred from experiment | unknown | MEROPS | Ortega J | Jomaa A et al.:Characterization of the autocle... (S01.273) | 19103920, |
| DEGP_ECOLI | 108 | QQQK.|.KFMA | inferred from experiment | unknown | MEROPS | Ortega J | Jomaa A et al.:Characterization of the autocle... (S01.273) | 19103920, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| DEGP_ECOLI | 95 | PFCQ.|.QGGQ | inferred from experiment | unknown | MEROPS | Ortega J | Jomaa A et al.:Characterization of the autocle... (S01.273) | 19103920, |
| DEGP_ECOLI | 108 | QQQK.|.KFMA | inferred from experiment | unknown | MEROPS | Ortega J | Jomaa A et al.:Characterization of the autocle... (S01.273) | 19103920, |