TopFIND 4.0

P10276: Retinoic acid receptor alpha

General Information

Protein names
- Retinoic acid receptor alpha
- RAR-alpha
- Nuclear receptor subfamily 1 group B member 1
Gene names RARA
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P10276

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASNSSSCPT PGGGHLNGYP VPPYAFFFPP MLGGLSPPGA LTTLQHQLPV SGYSTPSPAT 
        70         80         90        100        110        120 
IETQSSSSEE IVPSPPSPPP LPRIYKPCFV CQDKSSGYHY GVSACEGCKG FFRRSIQKNM 
       130        140        150        160        170        180 
VYTCHRDKNC IINKVTRNRC QYCRLQKCFE VGMSKESVRN DRNKKKKEVP KPECSESYTL 
       190        200        210        220        230        240 
TPEVGELIEK VRKAHQETFP ALCQLGKYTT NNSSEQRVSL DIDLWDKFSE LSTKCIIKTV 
       250        260        270        280        290        300 
EFAKQLPGFT TLTIADQITL LKAACLDILI LRICTRYTPE QDTMTFSDGL TLNRTQMHNA 
       310        320        330        340        350        360 
GFGPLTDLVF AFANQLLPLE MDDAETGLLS AICLICGDRQ DLEQPDRVDM LQEPLLEALK 
       370        380        390        400        410        420 
VYVRKRRPSR PHMFPKMLMK ITDLRSISAK GAERVITLKM EIPGSMPPLI QEMLENSEGL 
       430        440        450        460    
DTLSGQPGGG GRDGGGLAPP PGSCSPSLSP SSNRSSPATH SP

Isoforms

- Isoform Alpha-2 of Retinoic acid receptor alpha - Isoform Alpha-1-deltaBC of Retinoic acid receptor alpha

Sequence View

        10         20         30         40         50         60 
MASNSSSCPT PGGGHLNGYP VPPYAFFFPP MLGGLSPPGA LTTLQHQLPV SGYSTPSPAT 
        70         80         90        100        110        120 
IETQSSSSEE IVPSPPSPPP LPRIYKPCFV CQDKSSGYHY GVSACEGCKG FFRRSIQKNM 
       130        140        150        160        170        180 
VYTCHRDKNC IINKVTRNRC QYCRLQKCFE VGMSKESVRN DRNKKKKEVP KPECSESYTL 
       190        200        210        220        230        240 
TPEVGELIEK VRKAHQETFP ALCQLGKYTT NNSSEQRVSL DIDLWDKFSE LSTKCIIKTV 
       250        260        270        280        290        300 
EFAKQLPGFT TLTIADQITL LKAACLDILI LRICTRYTPE QDTMTFSDGL TLNRTQMHNA 
       310        320        330        340        350        360 
GFGPLTDLVF AFANQLLPLE MDDAETGLLS AICLICGDRQ DLEQPDRVDM LQEPLLEALK 
       370        380        390        400        410        420 
VYVRKRRPSR PHMFPKMLMK ITDLRSISAK GAERVITLKM EIPGSMPPLI QEMLENSEGL 
       430        440        450        460    
DTLSGQPGGG GRDGGGLAPP PGSCSPSLSP SSNRSSPATH SP         10         20         30         40         50         60 
MASNSSSCPT PGGGHLNGYP VPPYAFFFPP MLGGLSPPGA LTTLQHQLPV SGYSTPSPAT 
        70         80         90        100        110        120 
IETQSSSSEE IVPSPPSPPP LPRIYKPCFV CQDKSSGYHY GVSACEGCKG FFRRSIQKNM 
       130        140        150        160        170        180 
VYTCHRDKNC IINKVTRNRC QYCRLQKCFE VGMSKESVRN DRNKKKKEVP KPECSESYTL 
       190        200        210        220        230        240 
TPEVGELIEK VRKAHQETFP ALCQLGKYTT NNSSEQRVSL DIDLWDKFSE LSTKCIIKTV 
       250        260        270        280        290        300 
EFAKQLPGFT TLTIADQITL LKAACLDILI LRICTRYTPE QDTMTFSDGL TLNRTQMHNA 
       310        320        330        340        350        360 
GFGPLTDLVF AFANQLLPLE MDDAETGLLS AICLICGDRQ DLEQPDRVDM LQEPLLEALK 
       370        380        390        400        410        420 
VYVRKRRPSR PHMFPKMLMK ITDLRSISAK GAERVITLKM EIPGSMPPLI QEMLENSEGL 
       430        440        450        460    
DTLSGQPGGG GRDGGGLAPP PGSCSPSLSP SSNRSSPATH SP



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P10276-1-unknown MASNSS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P10276-1-unknown MASNSS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86965

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)