P10415: Apoptosis regulator Bcl-2
| Protein names | - Apoptosis regulator Bcl-2 |
|---|---|
| Gene names | BCL2 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P10415 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAHAGRTGYD NREIVMKYIH YKLSQRGYEW DAGDVGAAPP GAAPAPGIFS SQPGHTPHPA
70 80 90 100 110 120
ASRDPVARTS PLQTPAAPGA AAGPALSPVP PVVHLTLRQA GDDFSRRYRR DFAEMSSQLH
130 140 150 160 170 180
LTPFTARGRF ATVVEELFRD GVNWGRIVAF FEFGGVMCVE SVNREMSPLV DNIALWMTEY
190 200 210 220 230
LNRHLHTWIQ DNGGWDAFVE LYGPSMRPLF DFSWLSLKTL LSLALVGACI TLGAYLGHK
Isoforms
- Isoform Beta of Apoptosis regulator Bcl-2Sequence View
10 20 30 40 50 60
MAHAGRTGYD NREIVMKYIH YKLSQRGYEW DAGDVGAAPP GAAPAPGIFS SQPGHTPHPA
70 80 90 100 110 120
ASRDPVARTS PLQTPAAPGA AAGPALSPVP PVVHLTLRQA GDDFSRRYRR DFAEMSSQLH
130 140 150 160 170 180
LTPFTARGRF ATVVEELFRD GVNWGRIVAF FEFGGVMCVE SVNREMSPLV DNIALWMTEY
190 200 210 220 230
LNRHLHTWIQ DNGGWDAFVE LYGPSMRPLF DFSWLSLKTL LSLALVGACI TLGAYLGHK
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P10415-1-unknown | MAHAGR... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P10415-1-unknown | MAHAGR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68322 | |||
| P10415-35-unknown | VGAAPP... | 35 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1627 | |||
| P10415-35-unknown | VGAAPP... | 35 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137962 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...WDAGDV | 34 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1627 | |||
| ...WDAGDV | 34 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt120971 | |||
| ...YLGHK | 239 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CASP3_HUMAN | 34 | AGDV.|.VGAA | inferred from experiment | unknown | MEROPS | Hardwick JM | Cheng EH et al.:Conversion of Bcl-2 to a Bax-li... (C14.003) | 9395403, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|