P10746: Uroporphyrinogen-III synthase

General Information

Protein names	- Uroporphyrinogen-III synthase - UROIIIS - UROS - 4.2.1.75 - Hydroxymethylbilane hydrolyase cyclizing] - Uroporphyrinogen-III cosynthase
Gene names	UROS
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P10746

1 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI
        70         80         90        100        110        120
FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG
       130        140        150        160        170        180
NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL
       190        200        210        220        230        240
NSYYSQQGVP ASITFFSPSG LTYSLKHIQE LSGDNIDQIK FAAIGPTTAR ALAAQGLPVS
       250        260
CTAESPTPQA LATGIRKALQ PHGCC

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P10746-1-unknown	MKVLLL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P10746-1-unknown	MKVLLL...	1		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P10746-1-unknown	MKVLLL...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...QELSGD	213	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000414833
	...PHGCC	265	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)