P10747: T-cell-specific surface glycoprotein CD28

General Information

Protein names	- T-cell-specific surface glycoprotein CD28 - TP44 - CD28
Gene names	CD28
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P10747

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of T-cell-specific surface glycoprotein CD28 - Isoform 3 of T-cell-specific surface glycoprotein CD28 - Isoform 4 of T-cell-specific surface glycoprotein CD28 - Isoform 5 of T-cell-specific surface glycoprotein CD28 - Isoform 6 of T-cell-specific surface glycoprotein CD28 - Isoform 7 of T-cell-specific surface glycoprotein CD28

Sequence View

        10         20         30         40         50         60
MLRLLLALNL FPSIQVTGNK ILVKQSPMLV AYDNAVNLSC KYSYNLFSRE FRASLHKGLD
        70         80         90        100        110        120
SAVEVCVVYG NYSQQLQVYS KTGFNCDGKL GNESVTFYLQ NLYVNQTDIY FCKIEVMYPP
       130        140        150        160        170        180
PYLDNEKSNG TIIHVKGKHL CPSPLFPGPS KPFWVLVVVG GVLACYSLLV TVAFIIFWVR
       190        200        210        220
SKRSRLLHSD YMNMTPRRPG PTRKHYQPYA PPRDFAAYRS         10         20         30         40         50         60
MLRLLLALNL FPSIQVTGNK ILVKQSPMLV AYDNAVNLSC KYSYNLFSRE FRASLHKGLD
        70         80         90        100        110        120
SAVEVCVVYG NYSQQLQVYS KTGFNCDGKL GNESVTFYLQ NLYVNQTDIY FCKIEVMYPP
       130        140        150        160        170        180
PYLDNEKSNG TIIHVKGKHL CPSPLFPGPS KPFWVLVVVG GVLACYSLLV TVAFIIFWVR
       190        200        210        220
SKRSRLLHSD YMNMTPRRPG PTRKHYQPYA PPRDFAAYRS         10         20         30         40         50         60
MLRLLLALNL FPSIQVTGNK ILVKQSPMLV AYDNAVNLSC KYSYNLFSRE FRASLHKGLD
        70         80         90        100        110        120
SAVEVCVVYG NYSQQLQVYS KTGFNCDGKL GNESVTFYLQ NLYVNQTDIY FCKIEVMYPP
       130        140        150        160        170        180
PYLDNEKSNG TIIHVKGKHL CPSPLFPGPS KPFWVLVVVG GVLACYSLLV TVAFIIFWVR
       190        200        210        220
SKRSRLLHSD YMNMTPRRPG PTRKHYQPYA PPRDFAAYRS         10         20         30         40         50         60
MLRLLLALNL FPSIQVTGNK ILVKQSPMLV AYDNAVNLSC KYSYNLFSRE FRASLHKGLD
        70         80         90        100        110        120
SAVEVCVVYG NYSQQLQVYS KTGFNCDGKL GNESVTFYLQ NLYVNQTDIY FCKIEVMYPP
       130        140        150        160        170        180
PYLDNEKSNG TIIHVKGKHL CPSPLFPGPS KPFWVLVVVG GVLACYSLLV TVAFIIFWVR
       190        200        210        220
SKRSRLLHSD YMNMTPRRPG PTRKHYQPYA PPRDFAAYRS         10         20         30         40         50         60
MLRLLLALNL FPSIQVTGNK ILVKQSPMLV AYDNAVNLSC KYSYNLFSRE FRASLHKGLD
        70         80         90        100        110        120
SAVEVCVVYG NYSQQLQVYS KTGFNCDGKL GNESVTFYLQ NLYVNQTDIY FCKIEVMYPP
       130        140        150        160        170        180
PYLDNEKSNG TIIHVKGKHL CPSPLFPGPS KPFWVLVVVG GVLACYSLLV TVAFIIFWVR
       190        200        210        220
SKRSRLLHSD YMNMTPRRPG PTRKHYQPYA PPRDFAAYRS         10         20         30         40         50         60
MLRLLLALNL FPSIQVTGNK ILVKQSPMLV AYDNAVNLSC KYSYNLFSRE FRASLHKGLD
        70         80         90        100        110        120
SAVEVCVVYG NYSQQLQVYS KTGFNCDGKL GNESVTFYLQ NLYVNQTDIY FCKIEVMYPP
       130        140        150        160        170        180
PYLDNEKSNG TIIHVKGKHL CPSPLFPGPS KPFWVLVVVG GVLACYSLLV TVAFIIFWVR
       190        200        210        220
SKRSRLLHSD YMNMTPRRPG PTRKHYQPYA PPRDFAAYRS

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P10747-1-unknown	MLRLLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69919
P10747-1-unknown	MLRLLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69920
P10747-1-unknown	MLRLLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69921
P10747-1-unknown	MLRLLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69922
P10747-19-unknown	NKILVK...	19	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P10747-19-unknown	NKILVK...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112151
P10747-19-unknown	NKILVK...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112152
P10747-19-unknown	NKILVK...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112153
P10747-19-unknown	NKILVK...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112154
P10747-19-unknown	NKILVK...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112150

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AAYRS	220	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AAYRS	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65536
...AAYRS	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65538
...AAYRS	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65537
...AAYRS	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65541

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)