P10912: Growth hormone receptor

General Information

Protein names	- Growth hormone receptor - GH receptor - Somatotropin receptor - Growth hormone-binding protein - GH-binding protein - GHBP - Serum-binding protein
Gene names	GHR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P10912

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Growth hormone receptor - Isoform 3 of Growth hormone receptor - Isoform 4 of Growth hormone receptor

Sequence View

        10         20         30         40         50         60
MDLWQLLLTL ALAGSSDAFS GSEATAAILS RAPWSLQSVN PGLKTNSSKE PKFTKCRSPE
        70         80         90        100        110        120
RETFSCHWTD EVHHGTKNLG PIQLFYTRRN TQEWTQEWKE CPDYVSAGEN SCYFNSSFTS
       130        140        150        160        170        180
IWIPYCIKLT SNGGTVDEKC FSVDEIVQPD PPIALNWTLL NVSLTGIHAD IQVRWEAPRN
       190        200        210        220        230        240
ADIQKGWMVL EYELQYKEVN ETKWKMMDPI LTTSVPVYSL KVDKEYEVRV RSKQRNSGNY
       250        260        270        280        290        300
GEFSEVLYVT LPQMSQFTCE EDFYFPWLLI IIFGIFGLTV MLFVFLFSKQ QRIKMLILPP
       310        320        330        340        350        360
VPVPKIKGID PDLLKEGKLE EVNTILAIHD SYKPEFHSDD SWVEFIELDI DEPDEKTEES
       370        380        390        400        410        420
DTDRLLSSDH EKSHSNLGVK DGDSGRTSCC EPDILETDFN ANDIHEGTSE VAQPQRLKGE
       430        440        450        460        470        480
ADLLCLDQKN QNNSPYHDAC PATQQPSVIQ AEKNKPQPLP TEGAESTHQA AHIQLSNPSS
       490        500        510        520        530        540
LSNIDFYAQV SDITPAGSVV LSPGQKNKAG MSQCDMHPEM VSLCQENFLM DNAYFCEADA
       550        560        570        580        590        600
KKCIPVAPHI KVESHIQPSL NQEDIYITTE SLTTAAGRPG TGEHVPGSEM PVPDYTSIHI
       610        620        630
VQSPQGLILN ATALPLPDKE FLSSCGYVST DQLNKIMP         10         20         30         40         50         60
MDLWQLLLTL ALAGSSDAFS GSEATAAILS RAPWSLQSVN PGLKTNSSKE PKFTKCRSPE
        70         80         90        100        110        120
RETFSCHWTD EVHHGTKNLG PIQLFYTRRN TQEWTQEWKE CPDYVSAGEN SCYFNSSFTS
       130        140        150        160        170        180
IWIPYCIKLT SNGGTVDEKC FSVDEIVQPD PPIALNWTLL NVSLTGIHAD IQVRWEAPRN
       190        200        210        220        230        240
ADIQKGWMVL EYELQYKEVN ETKWKMMDPI LTTSVPVYSL KVDKEYEVRV RSKQRNSGNY
       250        260        270        280        290        300
GEFSEVLYVT LPQMSQFTCE EDFYFPWLLI IIFGIFGLTV MLFVFLFSKQ QRIKMLILPP
       310        320        330        340        350        360
VPVPKIKGID PDLLKEGKLE EVNTILAIHD SYKPEFHSDD SWVEFIELDI DEPDEKTEES
       370        380        390        400        410        420
DTDRLLSSDH EKSHSNLGVK DGDSGRTSCC EPDILETDFN ANDIHEGTSE VAQPQRLKGE
       430        440        450        460        470        480
ADLLCLDQKN QNNSPYHDAC PATQQPSVIQ AEKNKPQPLP TEGAESTHQA AHIQLSNPSS
       490        500        510        520        530        540
LSNIDFYAQV SDITPAGSVV LSPGQKNKAG MSQCDMHPEM VSLCQENFLM DNAYFCEADA
       550        560        570        580        590        600
KKCIPVAPHI KVESHIQPSL NQEDIYITTE SLTTAAGRPG TGEHVPGSEM PVPDYTSIHI
       610        620        630
VQSPQGLILN ATALPLPDKE FLSSCGYVST DQLNKIMP         10         20         30         40         50         60
MDLWQLLLTL ALAGSSDAFS GSEATAAILS RAPWSLQSVN PGLKTNSSKE PKFTKCRSPE
        70         80         90        100        110        120
RETFSCHWTD EVHHGTKNLG PIQLFYTRRN TQEWTQEWKE CPDYVSAGEN SCYFNSSFTS
       130        140        150        160        170        180
IWIPYCIKLT SNGGTVDEKC FSVDEIVQPD PPIALNWTLL NVSLTGIHAD IQVRWEAPRN
       190        200        210        220        230        240
ADIQKGWMVL EYELQYKEVN ETKWKMMDPI LTTSVPVYSL KVDKEYEVRV RSKQRNSGNY
       250        260        270        280        290        300
GEFSEVLYVT LPQMSQFTCE EDFYFPWLLI IIFGIFGLTV MLFVFLFSKQ QRIKMLILPP
       310        320        330        340        350        360
VPVPKIKGID PDLLKEGKLE EVNTILAIHD SYKPEFHSDD SWVEFIELDI DEPDEKTEES
       370        380        390        400        410        420
DTDRLLSSDH EKSHSNLGVK DGDSGRTSCC EPDILETDFN ANDIHEGTSE VAQPQRLKGE
       430        440        450        460        470        480
ADLLCLDQKN QNNSPYHDAC PATQQPSVIQ AEKNKPQPLP TEGAESTHQA AHIQLSNPSS
       490        500        510        520        530        540
LSNIDFYAQV SDITPAGSVV LSPGQKNKAG MSQCDMHPEM VSLCQENFLM DNAYFCEADA
       550        560        570        580        590        600
KKCIPVAPHI KVESHIQPSL NQEDIYITTE SLTTAAGRPG TGEHVPGSEM PVPDYTSIHI
       610        620        630
VQSPQGLILN ATALPLPDKE FLSSCGYVST DQLNKIMP

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P10912-1-unknown	MDLWQL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75970
P10912-1-unknown	MDLWQL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75971
P10912-1-unknown	MDLWQL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75972
P10912-19-unknown	FSGSEA...	19	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P10912-19-unknown	FSGSEA...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112186
P10912-19-unknown	FSGSEA...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112187

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PQMSQF	256	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PQMSQF	256	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92119
...PQMSQF	256	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92120
...PQMSQF	256	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92121
...NKIMP	638	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...NKIMP	638	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71590

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P10912: Growth hormone receptor

General Information

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates