TopFIND 4.0

P10964: DNA-directed RNA polymerase I subunit RPA190

General Information

Protein names
- DNA-directed RNA polymerase I subunit RPA190
- 2.7.7.6
- DNA-directed RNA polymerase I 190 kDa polypeptide
- A190
- DNA-directed RNA polymerase I largest subunit
Gene names RPA190
Organism Saccharomyces cerevisiae
Protease Family
Protease ID
Chromosome location
UniProt ID P10964

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDISKPVGSE ITSVDFGILT AKEIRNLSAK QITNPTVLDN LGHPVSGGLY DLALGAFLRN 
        70         80         90        100        110        120 
LCSTCGLDEK FCPGHQGHIE LPVPCYNPLF FNQLYIYLRA SCLFCHHFRL KSVEVHRYAC 
       130        140        150        160        170        180 
KLRLLQYGLI DESYKLDEIT LGSLNSSMYT DDEAIEDNED EMDGEGSKQS KDISSTLLNE 
       190        200        210        220        230        240 
LKSKRSEYVD MAIAKALSDG RTTERGSFTA TVNDERKKLV HEFHKKLLSR GKCDNCGMFS 
       250        260        270        280        290        300 
PKFRKDGFTK IFETALNEKQ ITNNRVKGFI RQDMIKKQKQ AKKLDGSNEA SANDEESFDV 
       310        320        330        340        350        360 
GRNPTTRPKT GSTYILSTEV KNILDTVFRK EQCVLQYVFH SRPNLSRKLV KADSFFMDVL 
       370        380        390        400        410        420 
VVPPTRFRLP SKLGEEVHEN SQNQLLSKVL TTSLLIRDLN DDLSKLQKDK VSLEDRRVIF 
       430        440        450        460        470        480 
SRLMNAFVTI QNDVNAFIDS TKAQGRTSGK VPIPGVKQAL EKKEGLFRKH MMGKRVNYAA 
       490        500        510        520        530        540 
RSVISPDPNI ETNEIGVPPV FAVKLTYPEP VTAYNIAELR QAVINGPDKW PGATQIQNED 
       550        560        570        580        590        600 
GSLVSLIGMS VEQRKALANQ LLTPSSNVST HTLNKKVYRH IKNRDVVLMN RQPTLHKASM 
       610        620        630        640        650        660 
MGHKVRVLPN EKTLRLHYAN TGAYNADFDG DEMNMHFPQN ENARAEALNL ANTDSQYLTP 
       670        680        690        700        710        720 
TSGSPVRGLI QDHISAGVWL TSKDSFFTRE QYQQYIYGCI RPEDGHTTRS KIVTLPPTIF 
       730        740        750        760        770        780 
KPYPLWTGKQ IITTVLLNVT PPDMPGINLI SKNKIKNEYW GKGSLENEVL FKDGALLCGI 
       790        800        810        820        830        840 
LDKSQYGASK YGIVHSLHEV YGPEVAAKVL SVLGRLFTNY ITATAFTCGM DDLRLTAEGN 
       850        860        870        880        890        900 
KWRTDILKTS VDTGREAAAE VTNLDKDTPA DDPELLKRLQ EILRDNNKSG ILDAVTSSKV 
       910        920        930        940        950        960 
NAITSQVVSK CVPDGTMKKF PCNSMQAMAL SGAKGSNVNV SQIMCLLGQQ ALEGRRVPVM 
       970        980        990       1000       1010       1020 
VSGKTLPSFK PYETDAMAGG YVKGRFYSGI KPQEYYFHCM AGREGLIDTA VKTSRSGYLQ 
      1030       1040       1050       1060       1070       1080 
RCLTKQLEGV HVSYDNSIRD ADGTLVQFMY GGDAIDITKE SHMTQFEFCL DNYYALLKKY 
      1090       1100       1110       1120       1130       1140 
NPSALIEHLD VESALKYSKK TLKYRKKHSK EPHYKQSVKY DPVLAKYNPA KYLGSVSENF 
      1150       1160       1170       1180       1190       1200 
QDKLESFLDK NSKLFKSSDG VNEKKFRALM QLKYMRSLIN PGEAVGIIAS QSVGEPSTQM 
      1210       1220       1230       1240       1250       1260 
TLNTFHFAGH GAANVTLGIP RLREIVMTAS AAIKTPQMTL PIWNDVSDEQ ADTFCKSISK 
      1270       1280       1290       1300       1310       1320 
VLLSEVIDKV IVTETTGTSN TAGGNAARSY VIHMRFFDNN EYSEEYDVSK EELQNVISNQ 
      1330       1340       1350       1360       1370       1380 
FIHLLEAAIV KEIKKQKRTT GPDIGVAVPR LQTDVANSSS NSKRLEEDND EEQSHKKTKQ 
      1390       1400       1410       1420       1430       1440 
AVSYDEPDED EIETMREAEK SSDEEGIDSD KESDSDSEDE DVDMNEQINK SIVEANNNMN 
      1450       1460       1470       1480       1490       1500 
KVQRDRQSAI ISHHRFITKY NFDDESGKWC EFKLELAADT EKLLMVNIVE EICRKSIIRQ 
      1510       1520       1530       1540       1550       1560 
IPHIDRCVHP EPENGKRVLV TEGVNFQAMW DQEAFIDVDG ITSNDVAAVL KTYGVEAARN 
      1570       1580       1590       1600       1610       1620 
TIVNEINNVF SRYAISVSFR HLDLIADMMT RQGTYLAFNR QGMETSTSSF MKMSYETTCQ 
      1630       1640       1650       1660    
FLTKAVLDNE REQLDSPSAR IVVGKLNNVG TGSFDVLAKV PNAA

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P10964-1-unknown MDISKP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VPNAA 1664 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)