P11086: Phenylethanolamine N-methyltransferase

General Information

Protein names	- Phenylethanolamine N-methyltransferase - PNMTase - 2.1.1.28 - Noradrenaline N-methyltransferase
Gene names	PNMT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P11086

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGADRSPNA GAAPDSAPGQ AAVASAYQRF EPRAYLRNNY APPRGDLCNP NGVGPWKLRC
        70         80         90        100        110        120
LAQTFATGEV SGRTLIDIGS GPTVYQLLSA CSHFEDITMT DFLEVNRQEL GRWLQEEPGA
       130        140        150        160        170        180
FNWSMYSQHA CLIEGKGECW QDKERQLRAR VKRVLPIDVH QPQPLGAGSP APLPADALVS
       190        200        210        220        230        240
AFCLEAVSPD LASFQRALDH ITTLLRPGGH LLLIGALEES WYLAGEARLT VVPVSEEEVR
       250        260        270        280
EALVRSGYKV RDLRTYIMPA HLQTGVDDVK GVFFAWAQKV GL

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P11086-1-unknown	MSGADR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P11086-16-	SAPGQA...	16		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P11086-99-unknown	MTDFLE...	99	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000377791

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...IEGKGE	137	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000464234
	...QKVGL	282	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)