TopFIND 4.0

P11161: E3 SUMO-protein ligase EGR2

General Information

Protein names
- E3 SUMO-protein ligase EGR2
- 2.3.2.-
- AT591
- E3 SUMO-protein transferase ERG2 {ECO:0000305}
- Early growth response protein 2
- EGR-2
- Zinc finger protein Krox-20
Gene names EGR2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P11161

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MMTAKAVDKI PVTLSGFVHQ LSDNIYPVED LAATSVTIFP NAELGGPFDQ MNGVAGDGMI 
        70         80         90        100        110        120 
NIDMTGEKRS LDLPYPSSFA PVSAPRNQTF TYMGKFSIDP QYPGASCYPE GIINIVSAGI 
       130        140        150        160        170        180 
LQGVTSPAST TASSSVTSAS PNPLATGPLG VCTMSQTQPD LDHLYSPPPP PPPYSGCAGD 
       190        200        210        220        230        240 
LYQDPSAFLS AATTSTSSSL AYPPPPSYPS PKPATDPGLF PMIPDYPGFF PSQCQRDLHG 
       250        260        270        280        290        300 
TAGPDRKPFP CPLDTLRVPP PLTPLSTIRN FTLGGPSAGV TGPGASGGSE GPRLPGSSSA 
       310        320        330        340        350        360 
AAAAAAAAAY NPHHLPLRPI LRPRKYPNRP SKTPVHERPY PCPAEGCDRR FSRSDELTRH 
       370        380        390        400        410        420 
IRIHTGHKPF QCRICMRNFS RSDHLTTHIR THTGEKPFAC DYCGRKFARS DERKRHTKIH 
       430        440        450        460        470    
LRQKERKSSA PSASVPAPST ASCSGGVQPG GTLCSSNSSS LGGGPLAPCS SRTRTP

Isoforms

- Isoform Short of E3 SUMO-protein ligase EGR2

Sequence View

        10         20         30         40         50         60 
MMTAKAVDKI PVTLSGFVHQ LSDNIYPVED LAATSVTIFP NAELGGPFDQ MNGVAGDGMI 
        70         80         90        100        110        120 
NIDMTGEKRS LDLPYPSSFA PVSAPRNQTF TYMGKFSIDP QYPGASCYPE GIINIVSAGI 
       130        140        150        160        170        180 
LQGVTSPAST TASSSVTSAS PNPLATGPLG VCTMSQTQPD LDHLYSPPPP PPPYSGCAGD 
       190        200        210        220        230        240 
LYQDPSAFLS AATTSTSSSL AYPPPPSYPS PKPATDPGLF PMIPDYPGFF PSQCQRDLHG 
       250        260        270        280        290        300 
TAGPDRKPFP CPLDTLRVPP PLTPLSTIRN FTLGGPSAGV TGPGASGGSE GPRLPGSSSA 
       310        320        330        340        350        360 
AAAAAAAAAY NPHHLPLRPI LRPRKYPNRP SKTPVHERPY PCPAEGCDRR FSRSDELTRH 
       370        380        390        400        410        420 
IRIHTGHKPF QCRICMRNFS RSDHLTTHIR THTGEKPFAC DYCGRKFARS DERKRHTKIH 
       430        440        450        460        470    
LRQKERKSSA PSASVPAPST ASCSGGVQPG GTLCSSNSSS LGGGPLAPCS SRTRTP



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P11161-1-unknown MMTAKA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P11161-51-unknown MNGVAG... 51 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73732

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RTRTP 476 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RTRTP 476 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt69350

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)