P11511: Aromatase

General Information

Protein names	- Aromatase - 1.14.14.14 {ECO:0000269\|PubMed:27702664} - CYPXIX - Cytochrome P-450AROM - Cytochrome P450 19A1 - Estrogen synthase
Gene names	CYP19A1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P11511

1 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI
        70         80         90        100        110        120
SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL
       130        140        150        160        170        180
GLQCIGMHEK GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLDRLEEVTN
       190        200        210        220        230        240
ESGYVDVLTL LRRVMLDTSN TLFLRIPLDE SAIVVKIQGY FDAWQALLIK PDIFFKISWL
       250        260        270        280        290        300
YKKYEKSVKD LKDAIEVLIA EKRRRISTEE KLEECMDFAT ELILAEKRGD LTRENVNQCI
       310        320        330        340        350        360
LEMLIAAPDT MSVSLFFMLF LIAKHPNVEE AIIKEIQTVI GERDIKIDDI QKLKVMENFI
       370        380        390        400        410        420
YESMRYQPVV DLVMRKALED DVIDGYPVKK GTNIILNIGR MHRLEFFPKP NEFTLENFAK
       430        440        450        460        470        480
NVPYRYFQPF GFGPRGCAGK YIAMVMMKAI LVTLLRRFHV KTLQGQCVES IQKIHDLSLH
       490        500
PDETKNMLEM IFTPRNSDRC LEH

Isoforms

- Isoform 2 of Aromatase

Sequence View

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Protein Neighborhood

Domains & Features

1 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P11511-1-unknown	MVLEML...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MVTVCA	164	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453318
...TVCAES	166	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000384389
...LKTHLD	172	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452872
...SWLYKK	242	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391139
...ATELIL	283	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453280
...CILEML	303	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454039
...RCLEH	503	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)