TopFIND 4.0

P11686: Pulmonary surfactant-associated protein C

General Information

Protein names
- Pulmonary surfactant-associated protein C
- SP-C
- Pulmonary surfactant-associated proteolipid SPL(Val)
- SP5
Gene names SFTPC
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P11686

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDVGSKEVLM ESPPDYSAAP RGRFGIPCCP VHLKRLLIVV VVVVLIVVVI VGALLMGLHM 
        70         80         90        100        110        120 
SQKHTEMVLE MSIGAPEAQQ RLALSEHLVT TATFSIGSTG LVVYDYQQLL IAYKPAPGTC 
       130        140        150        160        170        180 
CYIMKIAPES IPSLEALNRK VHNFQMECSL QAKPAVPTSK LGQAEGRDAG SAPSGGDPAF 
       190    
LGMAVNTLCG EVPLYYI

Isoforms

- Isoform 2 of Pulmonary surfactant-associated protein C

Sequence View

        10         20         30         40         50         60 
MDVGSKEVLM ESPPDYSAAP RGRFGIPCCP VHLKRLLIVV VVVVLIVVVI VGALLMGLHM 
        70         80         90        100        110        120 
SQKHTEMVLE MSIGAPEAQQ RLALSEHLVT TATFSIGSTG LVVYDYQQLL IAYKPAPGTC 
       130        140        150        160        170        180 
CYIMKIAPES IPSLEALNRK VHNFQMECSL QAKPAVPTSK LGQAEGRDAG SAPSGGDPAF 
       190    
LGMAVNTLCG EVPLYYI



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P11686-1-unknown MDVGSK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86425
    P11686-24-unknown FGIPCC... 24 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P11686-24-unknown FGIPCC... 24 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113597

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)