TopFIND 4.0

P11712: Cytochrome P450 2C9 {ECO:0000303|PubMed:8809086}

General Information

Protein names
- Cytochrome P450 2C9 {ECO:0000303|PubMed:8809086}
- 1.14.14.- {ECO:0000269|PubMed:12865317, ECO:0000269|PubMed:15766564, ECO:0000269|PubMed:19965576, ECO:0000269|PubMed:21576599, ECO:0000269|PubMed:7574697}
- (R)-limonene 6-monooxygenase
- 1.14.14.53 {ECO:0000269|PubMed:11950794}
- (S)-limonene 6-monooxygenase
- 1.14.14.51 {ECO:0000269|PubMed:11950794}
- (S)-limonene 7-monooxygenase
- 1.14.14.52 {ECO:0000269|PubMed:11950794}
- CYPIIC9
- Cholesterol 25-hydroxylase {ECO:0000303|PubMed:3079764}
- Cytochrome P-450MP
- Cytochrome P450 MP-4
- Cytochrome P450 MP-8
- Cytochrome P450 PB-1
- S-mephenytoin 4-hydroxylase {ECO:0000303|PubMed:3079764}
Gene names CYP2C9
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P11712

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDSLVVLVLC LSCLLLLSLW RQSSGRGKLP PGPTPLPVIG NILQIGIKDI SKSLTNLSKV 
        70         80         90        100        110        120 
YGPVFTLYFG LKPIVVLHGY EAVKEALIDL GEEFSGRGIF PLAERANRGF GIVFSNGKKW 
       130        140        150        160        170        180 
KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR CLVEELRKTK ASPCDPTFIL GCAPCNVICS 
       190        200        210        220        230        240 
IIFHKRFDYK DQQFLNLMEK LNENIKILSS PWIQICNNFS PIIDYFPGTH NKLLKNVAFM 
       250        260        270        280        290        300 
KSYILEKVKE HQESMDMNNP QDFIDCFLMK MEKEKHNQPS EFTIESLENT AVDLFGAGTE 
       310        320        330        340        350        360 
TTSTTLRYAL LLLLKHPEVT AKVQEEIERV IGRNRSPCMQ DRSHMPYTDA VVHEVQRYID 
       370        380        390        400        410        420 
LLPTSLPHAV TCDIKFRNYL IPKGTTILIS LTSVLHDNKE FPNPEMFDPH HFLDEGGNFK 
       430        440        450        460        470        480 
KSKYFMPFSA GKRICVGEAL AGMELFLFLT SILQNFNLKS LVDPKNLDTT PVVNGFASVP 
       490    
PFYQLCFIPV 

Isoforms

- Isoform 2 of Cytochrome P450 2C9

Sequence View

        10         20         30         40         50         60 
MDSLVVLVLC LSCLLLLSLW RQSSGRGKLP PGPTPLPVIG NILQIGIKDI SKSLTNLSKV 
        70         80         90        100        110        120 
YGPVFTLYFG LKPIVVLHGY EAVKEALIDL GEEFSGRGIF PLAERANRGF GIVFSNGKKW 
       130        140        150        160        170        180 
KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR CLVEELRKTK ASPCDPTFIL GCAPCNVICS 
       190        200        210        220        230        240 
IIFHKRFDYK DQQFLNLMEK LNENIKILSS PWIQICNNFS PIIDYFPGTH NKLLKNVAFM 
       250        260        270        280        290        300 
KSYILEKVKE HQESMDMNNP QDFIDCFLMK MEKEKHNQPS EFTIESLENT AVDLFGAGTE 
       310        320        330        340        350        360 
TTSTTLRYAL LLLLKHPEVT AKVQEEIERV IGRNRSPCMQ DRSHMPYTDA VVHEVQRYID 
       370        380        390        400        410        420 
LLPTSLPHAV TCDIKFRNYL IPKGTTILIS LTSVLHDNKE FPNPEMFDPH HFLDEGGNFK 
       430        440        450        460        470        480 
KSKYFMPFSA GKRICVGEAL AGMELFLFLT SILQNFNLKS LVDPKNLDTT PVVNGFASVP 
       490    
PFYQLCFIPV 



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Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P11712-1-unknown MDSLVV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CFIPV 490 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)