P11798: Calcium/calmodulin-dependent protein kinase type II subunit alpha
Protein names | - Calcium/calmodulin-dependent protein kinase type II subunit alpha - CaM kinase II subunit alpha - CaMK-II subunit alpha - 2.7.11.17 {ECO:0000250|UniProtKB:Q9UQM7} |
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Gene names | Camk2a |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P11798 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS ARDHQKLERE
70 80 90 100 110 120
ARICRLLKHP NIVRLHDSIS EEGHHYLIFD LVTGGELFED IVAREYYSEA DASHCIQQIL
130 140 150 160 170 180
EAVLHCHQMG VVHRDLKPEN LLLASKLKGA AVKLADFGLA IEVEGEQQAW FGFAGTPGYL
190 200 210 220 230 240
SPEVLRKDPY GKPVDLWACG VILYILLVGY PPFWDEDQHR LYQQIKAGAY DFPSPEWDTV
250 260 270 280 290 300
TPEAKDLINK MLTINPSKRI TAAEALKHPW ISHRSTVASC MHRQETVDCL KKFNARRKLK
310 320 330 340 350 360
GAILTTMLAT RNFSGGKSGG NKKNDGVKES SESTNTTIED EDTKVRKQEI IKVTEQLIEA
370 380 390 400 410 420
ISNGDFESYT KMCDPGMTAF EPEALGNLVE GLDFHRFYFE NLWSRNSKPV HTTILNPHIH
430 440 450 460 470
LMGDESACIA YIRITQYLDA GGIPRTAQSE ETRVWHRRDG KWQIVHFHRS GAPSVLPH
Isoforms
- Isoform Alpha KAP of Calcium/calmodulin-dependent protein kinase type II subunit alphaSequence View
10 20 30 40 50 60
MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS ARDHQKLERE
70 80 90 100 110 120
ARICRLLKHP NIVRLHDSIS EEGHHYLIFD LVTGGELFED IVAREYYSEA DASHCIQQIL
130 140 150 160 170 180
EAVLHCHQMG VVHRDLKPEN LLLASKLKGA AVKLADFGLA IEVEGEQQAW FGFAGTPGYL
190 200 210 220 230 240
SPEVLRKDPY GKPVDLWACG VILYILLVGY PPFWDEDQHR LYQQIKAGAY DFPSPEWDTV
250 260 270 280 290 300
TPEAKDLINK MLTINPSKRI TAAEALKHPW ISHRSTVASC MHRQETVDCL KKFNARRKLK
310 320 330 340 350 360
GAILTTMLAT RNFSGGKSGG NKKNDGVKES SESTNTTIED EDTKVRKQEI IKVTEQLIEA
370 380 390 400 410 420
ISNGDFESYT KMCDPGMTAF EPEALGNLVE GLDFHRFYFE NLWSRNSKPV HTTILNPHIH
430 440 450 460 470
LMGDESACIA YIRITQYLDA GGIPRTAQSE ETRVWHRRDG KWQIVHFHRS GAPSVLPH
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P11798-1-unknown | MATITC... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P11798-16-unknown | FEELGK... | 16 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29696 | |||
P11798-40-unknown | AAKIIN... | 40 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29697 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EEYQLF | 15 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29696 | |||
...AGQEYA | 39 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29697 | |||
...SVLPH | 478 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...SVLPH | 478 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt74266 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 15 | YQLF.|.FEEL | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> KCC2A_MOUSE @15 | ||
CATE_MOUSE | 39 | QEYA.|.AAKI | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> KCC2A_MOUSE @39 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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