P12382: ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255|HAMAP-Rule:MF_03184}
Protein names | - ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255|HAMAP-Rule:MF_03184} - ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184} - PFK-L - 2.7.1.11 {ECO:0000255|HAMAP-Rule:MF_03184} - 6-phosphofructokinase type B - Phosphofructo-1-kinase isozyme B - PFK-B - Phosphohexokinase {ECO:0000255|HAMAP-Rule:MF_03184} |
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Gene names | Pfkl |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P12382 |
4
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MATVDLEKLR MSGAGKAIGV LTSGGDAQGM NAAVRAVTRM GIYVGAKVFL IYEGYEGLVE
70 80 90 100 110 120
GGENIKPANW LSVSNIIQLG GTIIGSARCK AFTTREGRLA AAYNLLQHGI TNLCVIGGDG
130 140 150 160 170 180
SLTGANIFRN EWGSLLEELV KEGKISESTA QNYAHLTIAG LVGSIDNDFC GTDMTIGTDS
190 200 210 220 230 240
ALHRIMEVID AITTTAQSHQ RTFVLEVMGR HCGYLALVSA LASGADWLFI PEAPPEDGWE
250 260 270 280 290 300
NFMCERLGET RSRGSRLNII IIAEGAIDRH GKPISSSYVK DLVVQRLGFD TRVTVLGHVQ
310 320 330 340 350 360
RGGTPSAFDR ILSSKMGMEA VMALLEATPD TPACVVSLSG NQSVRLPLME CVQVTKDVQK
370 380 390 400 410 420
AMDEERFDEA IQLRGRSFEN NWKIYKLLAH QKVSKEKSNF SLAILNVGAP AAGMNAAVRS
430 440 450 460 470 480
AVRTGISEGH TVYIVHDGFE GLAKGQVQEV GWHDVAGWLG RGGSMLGTKR TLPKPHLEAI
490 500 510 520 530 540
VENLRTYNIH ALLVIGGFEA YEGVLQLVEA RGRYEELCIV MCVIPATISN NVPGTDFSLG
550 560 570 580 590 600
SDTAVNAAME SCDRIKQSAS GTKRRVFIVE TMGGYCGYLA TVTGIAVGAD AAYVFEDPFN
610 620 630 640 650 660
IHDLKANVEH MTEKMKTDIQ RGLVLRNEKC HEHYTTEFLY NLYSSEGRGV FDCRTNVLGH
670 680 690 700 710 720
LQQGGAPTPF DRNYGTKLGV KAMLWVSEKL RDVYRKGRVF ANAPDSACVI GLRKKVVAFS
730 740 750 760 770 780
PVTELKKETD FEHRMPREQW WLNLRLMLKM LAHYRISMAD YVSGELEHVT RRTLSIDKGF
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P12382-2-unknown | MATVDL... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
P12382-2-unknown | MATVDL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P12382-2-Acetylation | ATVDLE... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P12382-2-Acetylation | ATVDLE... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
P12382-538-unknown | SLGSDT... | 538 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29704 | |||
P12382-701-unknown | ANAPDS... | 701 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29705 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PGTDFS | 537 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29704 | |||
...KGRVFA | 700 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29705 | |||
...IDKGF | 780 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 537 | TDFS.|.SLGS | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> K6PL_MOUSE @537 | ||
CATE_MOUSE | 700 | RVFA.|.ANAP | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> K6PL_MOUSE @700 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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