P12695: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
| Protein names | - Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial - 2.3.1.12 - Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex - Pyruvate dehydrogenase complex component E2 - PDC-E2 - PDCE2 |
|---|---|
| Gene names | LAT1 |
| Organism | Saccharomyces cerevisiae |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P12695 |
2
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSAFVRVVPR ISRSSVLTRS LRLQLRCYAS YPEHTIIGMP ALSPTMTQGN LAAWTKKEGD
70 80 90 100 110 120
QLSPGEVIAE IETDKAQMDF EFQEDGYLAK ILVPEGTKDI PVNKPIAVYV EDKADVPAFK
130 140 150 160 170 180
DFKLEDSGSD SKTSTKAQPA EPQAEKKQEA PAEETKTSAP EAKKSDVAAP QGRIFASPLA
190 200 210 220 230 240
KTIALEKGIS LKDVHGTGPR GRITKADIES YLEKSSKQSS QTSGAAAATP AAATSSTTAG
250 260 270 280 290 300
SAPSPSSTAS YEDVPISTMR SIIGERLLQS TQGIPSYIVS SKISISKLLK LRQSLNATAN
310 320 330 340 350 360
DKYKLSINDL LVKAITVAAK RVPDANAYWL PNENVIRKFK NVDVSVAVAT PTGLLTPIVK
370 380 390 400 410 420
NCEAKGLSQI SNEIKELVKR ARINKLAPEE FQGGTICISN MGMNNAVNMF TSIINPPQST
430 440 450 460 470 480
ILAIATVERV AVEDAAAENG FSFDNQVTIT GTFDHRTIDG AKGAEFMKEL KTVIENPLEM
LL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P12695-28-unknown | YASYPE... | 28 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32121 | |||
| P12695-28-unknown | YASYPE... | 28 | unknown | Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... | 19837041 | ||||
| P12695-29-unknown | ASYPEH... | 29 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P12695-29-unknown | ASYPEH... | 29 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31989 | |||
| P12695-29-unknown | ASYPEH... | 29 | unknown | Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... | 19837041 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LQLRCY | 27 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32121 | |||
| ...QLRCYA | 28 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31989 | |||
| ...LEMLL | 482 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MPPB_YEAST | 27 | LRCY.|.YASY | inferred from experiment | unknown | MEROPS | Meisinger C | Vogtle FN et al.:Global analysis of the mitochon... (M24.026) | 19837041, |
| ICP55_YEAST | 28 | RCYA.|.ASYP | inferred from experiment | unknown | MEROPS | Meisinger C | Vogtle FN et al.:Global analysis of the mitochon... (M24.026) | 19837041, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|