TopFIND 4.0

P14416: D(2) dopamine receptor

General Information

Protein names
- D(2) dopamine receptor
- Dopamine D2 receptor
Gene names DRD2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P14416

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDPLNLSWYD DDLERQNWSR PFNGSDGKAD RPHYNYYATL LTLLIAVIVF GNVLVCMAVS 
        70         80         90        100        110        120 
REKALQTTTN YLIVSLAVAD LLVATLVMPW VVYLEVVGEW KFSRIHCDIF VTLDVMMCTA 
       130        140        150        160        170        180 
SILNLCAISI DRYTAVAMPM LYNTRYSSKR RVTVMISIVW VLSFTISCPL LFGLNNADQN 
       190        200        210        220        230        240 
ECIIANPAFV VYSSIVSFYV PFIVTLLVYI KIYIVLRRRR KRVNTKRSSR AFRAHLRAPL 
       250        260        270        280        290        300 
KGNCTHPEDM KLCTVIMKSN GSFPVNRRRV EAARRAQELE MEMLSSTSPP ERTRYSPIPP 
       310        320        330        340        350        360 
SHHQLTLPDP SHHGLHSTPD SPAKPEKNGH AKDHPKIAKI FEIQTMPNGK TRTSLKTMSR 
       370        380        390        400        410        420 
RKLSQQKEKK ATQMLAIVLG VFIICWLPFF ITHILNIHCD CNIPPVLYSA FTWLGYVNSA 
       430        440    
VNPIIYTTFN IEFRKAFLKI LHC

Isoforms

- Isoform 2 of D(2) dopamine receptor - Isoform 3 of D(2) dopamine receptor

Sequence View

        10         20         30         40         50         60 
MDPLNLSWYD DDLERQNWSR PFNGSDGKAD RPHYNYYATL LTLLIAVIVF GNVLVCMAVS 
        70         80         90        100        110        120 
REKALQTTTN YLIVSLAVAD LLVATLVMPW VVYLEVVGEW KFSRIHCDIF VTLDVMMCTA 
       130        140        150        160        170        180 
SILNLCAISI DRYTAVAMPM LYNTRYSSKR RVTVMISIVW VLSFTISCPL LFGLNNADQN 
       190        200        210        220        230        240 
ECIIANPAFV VYSSIVSFYV PFIVTLLVYI KIYIVLRRRR KRVNTKRSSR AFRAHLRAPL 
       250        260        270        280        290        300 
KGNCTHPEDM KLCTVIMKSN GSFPVNRRRV EAARRAQELE MEMLSSTSPP ERTRYSPIPP 
       310        320        330        340        350        360 
SHHQLTLPDP SHHGLHSTPD SPAKPEKNGH AKDHPKIAKI FEIQTMPNGK TRTSLKTMSR 
       370        380        390        400        410        420 
RKLSQQKEKK ATQMLAIVLG VFIICWLPFF ITHILNIHCD CNIPPVLYSA FTWLGYVNSA 
       430        440    
VNPIIYTTFN IEFRKAFLKI LHC         10         20         30         40         50         60 
MDPLNLSWYD DDLERQNWSR PFNGSDGKAD RPHYNYYATL LTLLIAVIVF GNVLVCMAVS 
        70         80         90        100        110        120 
REKALQTTTN YLIVSLAVAD LLVATLVMPW VVYLEVVGEW KFSRIHCDIF VTLDVMMCTA 
       130        140        150        160        170        180 
SILNLCAISI DRYTAVAMPM LYNTRYSSKR RVTVMISIVW VLSFTISCPL LFGLNNADQN 
       190        200        210        220        230        240 
ECIIANPAFV VYSSIVSFYV PFIVTLLVYI KIYIVLRRRR KRVNTKRSSR AFRAHLRAPL 
       250        260        270        280        290        300 
KGNCTHPEDM KLCTVIMKSN GSFPVNRRRV EAARRAQELE MEMLSSTSPP ERTRYSPIPP 
       310        320        330        340        350        360 
SHHQLTLPDP SHHGLHSTPD SPAKPEKNGH AKDHPKIAKI FEIQTMPNGK TRTSLKTMSR 
       370        380        390        400        410        420 
RKLSQQKEKK ATQMLAIVLG VFIICWLPFF ITHILNIHCD CNIPPVLYSA FTWLGYVNSA 
       430        440    
VNPIIYTTFN IEFRKAFLKI LHC



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P14416-1-unknown MDPLNL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P14416-1-unknown MDPLNL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73236
    P14416-1-unknown MDPLNL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73237

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)