TopFIND 4.0

P14598: Neutrophil cytosol factor 1

General Information

Protein names
- Neutrophil cytosol factor 1
- NCF-1
- 47 kDa autosomal chronic granulomatous disease protein
- 47 kDa neutrophil oxidase factor
- NCF-47K
- Neutrophil NADPH oxidase factor 1
- Nox organizer 2
- Nox-organizing protein 2
- SH3 and PX domain-containing protein 1A
- p47-phox
Gene names NCF1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P14598

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGDTFIRHIA LLGFEKRFVP SQHYVYMFLV KWQDLSEKVV YRRFTEIYEF HKTLKEMFPI 
        70         80         90        100        110        120 
EAGAINPENR IIPHLPAPKW FDGQRAAENR QGTLTEYCST LMSLPTKISR CPHLLDFFKV 
       130        140        150        160        170        180 
RPDDLKLPTD NQTKKPETYL MPKDGKSTAT DITGPIILQT YRAIANYEKT SGSEMALSTG 
       190        200        210        220        230        240 
DVVEVVEKSE SGWWFCQMKA KRGWIPASFL EPLDSPDETE DPEPNYAGEP YVAIKAYTAV 
       250        260        270        280        290        300 
EGDEVSLLEG EAVEVIHKLL DGWWVIRKDD VTGYFPSMYL QKSGQDVSQA QRQIKRGAPP 
       310        320        330        340        350        360 
RRSSIRNAHS IHQRSRKRLS QDAYRRNSVR FLQQRRRQAR PGPQSPGSPL EEERQTQRSK 
       370        380        390    
PQPAVPPRPS ADLILNRCSE STKRKLASAV 

Isoforms

- Isoform 2 of Neutrophil cytosol factor 1 - Isoform 2 of Neutrophil cytosol factor 1

Sequence View

        10         20         30         40         50         60 
MGDTFIRHIA LLGFEKRFVP SQHYVYMFLV KWQDLSEKVV YRRFTEIYEF HKTLKEMFPI 
        70         80         90        100        110        120 
EAGAINPENR IIPHLPAPKW FDGQRAAENR QGTLTEYCST LMSLPTKISR CPHLLDFFKV 
       130        140        150        160        170        180 
RPDDLKLPTD NQTKKPETYL MPKDGKSTAT DITGPIILQT YRAIANYEKT SGSEMALSTG 
       190        200        210        220        230        240 
DVVEVVEKSE SGWWFCQMKA KRGWIPASFL EPLDSPDETE DPEPNYAGEP YVAIKAYTAV 
       250        260        270        280        290        300 
EGDEVSLLEG EAVEVIHKLL DGWWVIRKDD VTGYFPSMYL QKSGQDVSQA QRQIKRGAPP 
       310        320        330        340        350        360 
RRSSIRNAHS IHQRSRKRLS QDAYRRNSVR FLQQRRRQAR PGPQSPGSPL EEERQTQRSK 
       370        380        390    
PQPAVPPRPS ADLILNRCSE STKRKLASAV          10         20         30         40         50         60 
MGDTFIRHIA LLGFEKRFVP SQHYVYMFLV KWQDLSEKVV YRRFTEIYEF HKTLKEMFPI 
        70         80         90        100        110        120 
EAGAINPENR IIPHLPAPKW FDGQRAAENR QGTLTEYCST LMSLPTKISR CPHLLDFFKV 
       130        140        150        160        170        180 
RPDDLKLPTD NQTKKPETYL MPKDGKSTAT DITGPIILQT YRAIANYEKT SGSEMALSTG 
       190        200        210        220        230        240 
DVVEVVEKSE SGWWFCQMKA KRGWIPASFL EPLDSPDETE DPEPNYAGEP YVAIKAYTAV 
       250        260        270        280        290        300 
EGDEVSLLEG EAVEVIHKLL DGWWVIRKDD VTGYFPSMYL QKSGQDVSQA QRQIKRGAPP 
       310        320        330        340        350        360 
RRSSIRNAHS IHQRSRKRLS QDAYRRNSVR FLQQRRRQAR PGPQSPGSPL EEERQTQRSK 
       370        380        390    
PQPAVPPRPS ADLILNRCSE STKRKLASAV 



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)