P14778: Interleukin-1 receptor type 1

General Information

Protein names	- Interleukin-1 receptor type 1 - IL-1R-1 - IL-1RT-1 - IL-1RT1 - CD121 antigen-like family member A - Interleukin-1 receptor alpha - IL-1R-alpha - Interleukin-1 receptor type I - p80 - CD121a - Interleukin-1 receptor type 1, membrane form - mIL-1R1 - mIL-1RI - Interleukin-1 receptor type 1, soluble form - sIL-1R1 - sIL-1RI
Gene names	IL1R1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P14778

2 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKVLLRLICF IALLISSLEA DKCKEREEKI ILVSSANEID VRPCPLNPNE HKGTITWYKD
        70         80         90        100        110        120
DSKTPVSTEQ ASRIHQHKEK LWFVPAKVED SGHYYCVVRN SSYCLRIKIS AKFVENEPNL
       130        140        150        160        170        180
CYNAQAIFKQ KLPVAGDGGL VCPYMEFFKN ENNELPKLQW YKDCKPLLLD NIHFSGVKDR
       190        200        210        220        230        240
LIVMNVAEKH RGNYTCHASY TYLGKQYPIT RVIEFITLEE NKPTRPVIVS PANETMEVDL
       250        260        270        280        290        300
GSQIQLICNV TGQLSDIAYW KWNGSVIDED DPVLGEDYYS VENPANKRRS TLITVLNISE
       310        320        330        340        350        360
IESRFYKHPF TCFAKNTHGI DAAYIQLIYP VTNFQKHMIG ICVTLTVIIV CSVFIYKIFK
       370        380        390        400        410        420
IDIVLWYRDS CYDFLPIKAS DGKTYDAYIL YPKTVGEGST SDCDIFVFKV LPEVLEKQCG
       430        440        450        460        470        480
YKLFIYGRDD YVGEDIVEVI NENVKKSRRL IIILVRETSG FSWLGGSSEE QIAMYNALVQ
       490        500        510        520        530        540
DGIKVVLLEL EKIQDYEKMP ESIKFIKQKH GAIRWSGDFT QGPQSAKTRF WKNVRYHMPV
       550        560
QRRSPSSKHQ LLSPATKEKL QREAHVPLG

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14778-18-unknown	LEADKC...	18		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14778-145-unknown	MEFFKN...	145		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000410461

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...	0	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QHKEKL	80	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401646
...SYCLRI	106	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411627
...SAKFVE	114	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393296
...KDRLIV	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000408101
...EVINEN	442	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410461
...HVPLG	569	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)