P14784: Interleukin-2 receptor subunit beta

General Information

Protein names	- Interleukin-2 receptor subunit beta - IL-2 receptor subunit beta - IL-2R subunit beta - IL-2RB - High affinity IL-2 receptor subunit beta - Interleukin-15 receptor subunit beta {ECO:0000312\|HGNC:HGNC:6009} - p70-75 - p75 - CD122
Gene names	IL2RB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P14784

1 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAPALSWRL PLLILLLPLA TSWASAAVNG TSQFTCFYNS RANISCVWSQ DGALQDTSCQ
        70         80         90        100        110        120
VHAWPDRRRW NQTCELLPVS QASWACNLIL GAPDSQKLTT VDIVTLRVLC REGVRWRVMA
       130        140        150        160        170        180
IQDFKPFENL RLMAPISLQV VHVETHRCNI SWEISQASHY FERHLEFEAR TLSPGHTWEE
       190        200        210        220        230        240
APLLTLKQKQ EWICLETLTP DTQYEFQVRV KPLQGEFTTW SPWSQPLAFR TKPAALGKDT
       250        260        270        280        290        300
IPWLGHLLVG LSGAFGFIIL VYLLINCRNT GPWLKKVLKC NTPDPSKFFS QLSSEHGGDV
       310        320        330        340        350        360
QKWLSSPFPS SSFSPGGLAP EISPLEVLER DKVTQLLLQQ DKVPEPASLS SNHSLTSCFT
       370        380        390        400        410        420
NQGYFFFHLP DALEIEACQV YFTYDPYSEE DPDEGVAGAP TGSSPQPLQP LSGEDDAYCT
       430        440        450        460        470        480
FPSRDDLLLF SPSLLGGPSP PSTAPGGSGA GEERMPPSLQ ERVPRDWDPQ PLGPPTPGVP
       490        500        510        520        530        540
DLVDFQPPPE LVLREAGEEV PDAGPREGVS FPWSRPPGQG EFRALNARLP LNTDAYLSLQ
       550
ELQGQDPTHL V

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14784-27-unknown	AVNGTS...	27		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...WACNLI	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401020
...HVETHR	146	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402685
...LTLKQK	188	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403731
...PTHLV	551	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)