TopFIND 4.0

P14891: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 {ECO:0000303|PubMed:7588795, ECO:0000303|PubMed:8302869}

General Information

Protein names
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 {ECO:0000303|PubMed:7588795, ECO:0000303|PubMed:8302869}
- AtHMGR1 {ECO:0000303|PubMed:7588795, ECO:0000303|PubMed:8302869}
- HMG-CoA reductase 1 {ECO:0000303|PubMed:7588795, ECO:0000303|PubMed:8302869}
- 1.1.1.34 {ECO:0000255|PROSITE-ProRule:PRU10003}
Gene names HMG1
Organism Arabidopsis thaliana
Protease Family
Protease ID
Chromosome location
UniProt ID P14891

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLRRRPPKP PVTNNNNSNG SFRSYQPRTS DDDHRRRATT IAPPPKASDA LPLPLYLTNA 
        70         80         90        100        110        120 
VFFTLFFSVA YYLLHRWRDK IRYNTPLHVV TITELGAIIA LIASFIYLLG FFGIDFVQSF 
       130        140        150        160        170        180 
ISRASGDAWD LADTIDDDDH RLVTCSPPTP IVSVAKLPNP EPIVTESLPE EDEEIVKSVI 
       190        200        210        220        230        240 
DGVIPSYSLE SRLGDCKRAA SIRREALQRV TGRSIEGLPL DGFDYESILG QCCEMPVGYI 
       250        260        270        280        290        300 
QIPVGIAGPL LLDGYEYSVP MATTEGCLVA STNRGCKAMF ISGGATSTVL KDGMTRAPVV 
       310        320        330        340        350        360 
RFASARRASE LKFFLENPEN FDTLAVVFNR SSRFARLQSV KCTIAGKNAY VRFCCSTGDA 
       370        380        390        400        410        420 
MGMNMVSKGV QNVLEYLTDD FPDMDVIGIS GNFCSDKKPA AVNWIEGRGK SVVCEAVIRG 
       430        440        450        460        470        480 
EIVNKVLKTS VAALVELNML KNLAGSAVAG SLGGFNAHAS NIVSAVFIAT GQDPAQNVES 
       490        500        510        520        530        540 
SQCITMMEAI NDGKDIHISV TMPSIEVGTV GGGTQLASQS ACLNLLGVKG ASTESPGMNA 
       550        560        570        580        590    
RRLATIVAGA VLAGELSLMS AIAAGQLVRS HMKYNRSSRD ISGATTTTTT TT

Isoforms

- Isoform Long of 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

Sequence View

        10         20         30         40         50         60 
MDLRRRPPKP PVTNNNNSNG SFRSYQPRTS DDDHRRRATT IAPPPKASDA LPLPLYLTNA 
        70         80         90        100        110        120 
VFFTLFFSVA YYLLHRWRDK IRYNTPLHVV TITELGAIIA LIASFIYLLG FFGIDFVQSF 
       130        140        150        160        170        180 
ISRASGDAWD LADTIDDDDH RLVTCSPPTP IVSVAKLPNP EPIVTESLPE EDEEIVKSVI 
       190        200        210        220        230        240 
DGVIPSYSLE SRLGDCKRAA SIRREALQRV TGRSIEGLPL DGFDYESILG QCCEMPVGYI 
       250        260        270        280        290        300 
QIPVGIAGPL LLDGYEYSVP MATTEGCLVA STNRGCKAMF ISGGATSTVL KDGMTRAPVV 
       310        320        330        340        350        360 
RFASARRASE LKFFLENPEN FDTLAVVFNR SSRFARLQSV KCTIAGKNAY VRFCCSTGDA 
       370        380        390        400        410        420 
MGMNMVSKGV QNVLEYLTDD FPDMDVIGIS GNFCSDKKPA AVNWIEGRGK SVVCEAVIRG 
       430        440        450        460        470        480 
EIVNKVLKTS VAALVELNML KNLAGSAVAG SLGGFNAHAS NIVSAVFIAT GQDPAQNVES 
       490        500        510        520        530        540 
SQCITMMEAI NDGKDIHISV TMPSIEVGTV GGGTQLASQS ACLNLLGVKG ASTESPGMNA 
       550        560        570        580        590    
RRLATIVAGA VLAGELSLMS AIAAGQLVRS HMKYNRSSRD ISGATTTTTT TT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P14891-1-unknown MDLRRR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P14891-1-unknown MDLRRR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt101205

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TTTTT 592 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TTTTT 592 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt72690

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)