P14923: Junction plakoglobin

General Information

Protein names	- Junction plakoglobin - Catenin gamma - Desmoplakin III - Desmoplakin-3
Gene names	JUP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P14923

1 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEVMNLMEQP IKVTEWQQTY TYDSGIHSGA NTCVPSVSSK GIMEEDEACG RQYTLKKTTT
        70         80         90        100        110        120
YTQGVPPSQG DLEYQMSTTA RAKRVREAMC PGVSGEDSSL LLATQVEGQA TNLQRLAEPS
       130        140        150        160        170        180
QLLKSAIVHL INYQDDAELA TRALPELTKL LNDEDPVVVT KAAMIVNQLS KKEASRRALM
       190        200        210        220        230        240
GSPQLVAAVV RTMQNTSDLD TARCTTSILH NLSHHREGLL AIFKSGGIPA LVRMLSSPVE
       250        260        270        280        290        300
SVLFYAITTL HNLLLYQEGA KMAVRLADGL QKMVPLLNKN NPKFLAITTD CLQLLAYGNQ
       310        320        330        340        350        360
ESKLIILANG GPQALVQIMR NYSYEKLLWT TSRVLKVLSV CPSNKPAIVE AGGMQALGKH
       370        380        390        400        410        420
LTSNSPRLVQ NCLWTLRNLS DVATKQEGLE SVLKILVNQL SVDDVNVLTC ATGTLSNLTC
       430        440        450        460        470        480
NNSKNKTLVT QNSGVEALIH AILRAGDKDD ITEPAVCALR HLTSRHPEAE MAQNSVRLNY
       490        500        510        520        530        540
GIPAIVKLLN QPNQWPLVKA TIGLIRNLAL CPANHAPLQE AAVIPRLVQL LVKAHQDAQR
       550        560        570        580        590        600
HVAAGTQQPY TDGVRMEEIV EGCTGALHIL ARDPMNRMEI FRLNTIPLFV QLLYSSVENI
       610        620        630        640        650        660
QRVAAGVLCE LAQDKEAADA IDAEGASAPL MELLHSRNEG TATYAAAVLF RISEDKNPDY
       670        680        690        700        710        720
RKRVSVELTN SLFKHDPAAW EAAQSMIPIN EPYGDDMDAT YRPMYSSDVP LDPLEMHMDM
       730        740
DGDYPIDTYS DGLRPPYPTA DHMLA

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14923-1-Acetylation	MEVMNL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14923-1-Acetylation	MEVMNL...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AKRVRE	86	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000409948
...AKRVRE	86	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456298
...LLLATQ	104	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468347
...LVRMLS	235	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401034
...LVRMLS	235	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454917
...KMVPLL	276	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411449
...KMVPLL	276	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455424
...CLQLLA	295	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394146
...CLQLLA	295	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456770
...QLLAYG	297	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000389886
...QLLAYG	297	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455782
...DHMLA	745	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)