TopFIND 4.0

P15005: 5-methylcytosine-specific restriction enzyme B

General Information

Protein names
- 5-methylcytosine-specific restriction enzyme B
- 3.1.21.-
- EcoKMcrBC
Gene names mcrB
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P15005

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MESIQPWIEK FIKQAQQQRS QSTKDYPTSY RNLRVKLSFG YGNFTSIPWF AFLGEGQEAS 
        70         80         90        100        110        120 
NGIYPVILYY KDFDELVLAY GISDTNEPHA QWQFSSDIPK TIAEYFQATS GVYPKKYGQS 
       130        140        150        160        170        180 
YYACSQKVSQ GIDYTRFASM LDNIINDYKL IFNSGKSVIP PMSKTESYCL EDALNDLFIP 
       190        200        210        220        230        240 
ETTIETILKR LTIKKNIILQ GPPGVGKTFV ARRLAYLLTG EKAPQRVNMV QFHQSYSYED 
       250        260        270        280        290        300 
FIQGYRPNGV GFRRKDGIFY NFCQQAKEQP EKKYIFIIDE INRANLSKVF GEVMMLMEHD 
       310        320        330        340        350        360 
KRGENWSVPL TYSENDEERF YVPENVYIIG LMNTADRSLA VVDYALRRRF SFIDIEPGFD 
       370        380        390        400        410        420 
TPQFRNFLLN KKAEPSFVES LCQKMNELNQ EISKEATILG KGFRIGHSYF CCGLEDGTSP 
       430        440        450    
DTQWLNEIVM TDIAPLLEEY FFDDPYKQQK WTNKLLGDS

Isoforms

- Isoform 33 kDa of 5-methylcytosine-specific restriction enzyme B

Sequence View

        10         20         30         40         50         60 
MESIQPWIEK FIKQAQQQRS QSTKDYPTSY RNLRVKLSFG YGNFTSIPWF AFLGEGQEAS 
        70         80         90        100        110        120 
NGIYPVILYY KDFDELVLAY GISDTNEPHA QWQFSSDIPK TIAEYFQATS GVYPKKYGQS 
       130        140        150        160        170        180 
YYACSQKVSQ GIDYTRFASM LDNIINDYKL IFNSGKSVIP PMSKTESYCL EDALNDLFIP 
       190        200        210        220        230        240 
ETTIETILKR LTIKKNIILQ GPPGVGKTFV ARRLAYLLTG EKAPQRVNMV QFHQSYSYED 
       250        260        270        280        290        300 
FIQGYRPNGV GFRRKDGIFY NFCQQAKEQP EKKYIFIIDE INRANLSKVF GEVMMLMEHD 
       310        320        330        340        350        360 
KRGENWSVPL TYSENDEERF YVPENVYIIG LMNTADRSLA VVDYALRRRF SFIDIEPGFD 
       370        380        390        400        410        420 
TPQFRNFLLN KKAEPSFVES LCQKMNELNQ EISKEATILG KGFRIGHSYF CCGLEDGTSP 
       430        440        450    
DTQWLNEIVM TDIAPLLEEY FFDDPYKQQK WTNKLLGDS



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P15005-1-unknown MESIQP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P15005-162-unknown MSKTES... 162 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80663

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLGDS 459 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LLGDS 459 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76281

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)