TopFIND 4.0

P15018: Leukemia inhibitory factor

General Information

Protein names
- Leukemia inhibitory factor
- LIF
- Differentiation-stimulating factor
- D factor
- Melanoma-derived LPL inhibitor
- MLPLI
- Emfilermin
Gene names LIF
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P15018

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKVLAAGVVP LLLVLHWKHG AGSPLPITPV NATCAIRHPC HNNLMNQIRS QLAQLNGSAN 
        70         80         90        100        110        120 
ALFILYYTAQ GEPFPNNLDK LCGPNVTDFP PFHANGTEKA KLVELYRIVV YLGTSLGNIT 
       130        140        150        160        170        180 
RDQKILNPSA LSLHSKLNAT ADILRGLLSN VLCRLCSKYH VGHVDVTYGP DTSGKDVFQK 
       190        200    
KKLGCQLLGK YKQIIAVLAQ AF

Isoforms

- Isoform 2 of Leukemia inhibitory factor

Sequence View

        10         20         30         40         50         60 
MKVLAAGVVP LLLVLHWKHG AGSPLPITPV NATCAIRHPC HNNLMNQIRS QLAQLNGSAN 
        70         80         90        100        110        120 
ALFILYYTAQ GEPFPNNLDK LCGPNVTDFP PFHANGTEKA KLVELYRIVV YLGTSLGNIT 
       130        140        150        160        170        180 
RDQKILNPSA LSLHSKLNAT ADILRGLLSN VLCRLCSKYH VGHVDVTYGP DTSGKDVFQK 
       190        200    
KKLGCQLLGK YKQIIAVLAQ AF



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P15018-23-unknown SPLPIT... 23 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LAQAF 202 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)