P15085: Carboxypeptidase A1

General Information

Protein names	- Carboxypeptidase A1 - 3.4.17.1
Gene names	CPA1
Organism	Homo sapiens
Protease Family
Protease ID	M14.001
Chromosome location
UniProt ID	P15085

2 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRGLLVLSVL LGAVFGKEDF VGHQVLRISV ADEAQVQKVK ELEDLEHLQL DFWRGPAHPG
        70         80         90        100        110        120
SPIDVRVPFP SIQAVKIFLE SHGISYETMI EDVQSLLDEE QEQMFAFRSR ARSTDTFNYA
       130        140        150        160        170        180
TYHTLEEIYD FLDLLVAENP HLVSKIQIGN TYEGRPIYVL KFSTGGSKRP AIWIDTGIHS
       190        200        210        220        230        240
REWVTQASGV WFAKKITQDY GQDAAFTAIL DTLDIFLEIV TNPDGFAFTH STNRMWRKTR
       250        260        270        280        290        300
SHTAGSLCIG VDPNRNWDAG FGLSGASSNP CSETYHGKFA NSEVEVKSIV DFVKDHGNIK
       310        320        330        340        350        360
AFISIHSYSQ LLMYPYGYKT EPVPDQDELD QLSKAAVTAL ASLYGTKFNY GSIIKAIYQA
       370        380        390        400        410
SGSTIDWTYS QGIKYSFTFE LRDTGRYGFL LPASQIIPTA KETWLALLTI MEHTLNHPY

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P15085-89-unknown	MIEDVQ...	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000420218
P15085-89-unknown	MIEDVQ...	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419408
P15085-89-unknown	MIEDVQ...	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419497
P15085-89-unknown	MIEDVQ...	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463157
P15085-89-unknown	MIEDVQ...	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462257
P15085-89-unknown	MIEDVQ...	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462357
P15085-111-unknown	ARSTDT...	111	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P15085-111-unknown	ARSTDT...	111	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16304

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AFRSRA	110	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16304
...ASGVWF	191	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000420218
...ASGVWF	191	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463157
...AAVTAL	339	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475021
...AAVTAL	339	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000474175
...IIKAIY	357	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419408
...IIKAIY	357	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462257
...LNHPY	419	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
KLK4_HUMAN	110	RSRA.\|.ARST	inferred from experiment	unknown	MEROPS	Nelson PS	Matsumura M et al.:Substrates of the prostate-spec... (S01.251)	15389820,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)