TopFIND 4.0

P15390: Sodium channel protein type 4 subunit alpha

General Information

Protein names
- Sodium channel protein type 4 subunit alpha
- Mu-1
- SkM1 {ECO:0000303|PubMed:9613589}
- Sodium channel protein skeletal muscle subunit alpha
- Sodium channel protein type IV subunit alpha
- Voltage-gated sodium channel subunit alpha Nav1.4
Gene names Scn4a
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P15390

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASSSLPNLV PPGPHCLRPF TPESLAAIEQ RAVEEEARLQ RNKQMEIEEP ERKPRSDLEA 
        70         80         90        100        110        120 
GKNLPLIYGD PPPEVIGIPL EDLDPYYSDK KTFIVLNKGK AIFRFSATPA LYLLSPFSIV 
       130        140        150        160        170        180 
RRVAIKVLIH ALFSMFIMIT ILTNCVFMTM SNPPSWSKHV EYTFTGIYTF ESLIKMLARG 
       190        200        210        220        230        240 
FCIDDFTFLR DPWNWLDFSV ITMAYVTEFV DLGNISALRT FRVLRALKTI TVIPGLKTIV 
       250        260        270        280        290        300 
GALIQSVKKL SDVMILTVFC LSVFALVGLQ LFMGNLRQKC VRWPPPMNDT NTTWYGNDTW 
       310        320        330        340        350        360 
YSNDTWYGND TWYINDTWNS QESWAGNSTF DWEAYINDEG NFYFLEGSND ALLCGNSSDA 
       370        380        390        400        410        420 
GHCPEGYECI KAGRNPNYGY TSYDTFSWAF LALFRLMTQD YWENLFQLTL RAAGKTYMIF 
       430        440        450        460        470        480 
FVVIIFLGSF YLINLILAVV AMAYAEQNEA TLAEDQEKEE EFQQMLEKYK KHQEELEKAK 
       490        500        510        520        530        540 
AAQALESGEE ADGDPTHNKD CNGSLDASGE KGPPRPSCSA DSAISDAMEE LEEAHQKCPP 
       550        560        570        580        590        600 
WWYKCAHKVL IWNCCAPWVK FKHIIYLIVM DPFVDLGITI CIVLNTLFMA MEHYPMTEHF 
       610        620        630        640        650        660 
DNVLSVGNLV FTGIFTAEMV LKLIAMDPYE YFQQGWNIFD SFIVTLSLVE LGLANVQGLS 
       670        680        690        700        710        720 
VLRSFRLLRV FKLAKSWPTL NMLIKIIGNS VGALGNLTLV LAIIVFIFAV VGMQLFGKSY 
       730        740        750        760        770        780 
KECVCKIASD CNLPRWHMND FFHSFLIVFR ILCGEWIETM WDCMEVAGQA MCLTVFLMVM 
       790        800        810        820        830        840 
VIGNLVVLNL FLALLLSSFS ADSLAASDED GEMNNLQIAI GRIKWGIGFA KTFLLGLLRG 
       850        860        870        880        890        900 
KILSPKEIIL SLGEPGGAGE NAEESTPEDE KKEPPPEDKE LKDNHILNHV GLTDGPRSSI 
       910        920        930        940        950        960 
ELDHLNFINN PYLTIQVPIA SEESDLEMPT EEETDAFSEP EDIKKPLQPL YDGNSSVCST 
       970        980        990       1000       1010       1020 
ADYKPPEEDP EEQAEENPEG EQPEECFTEA CVKRCPCLYV DISQGRGKMW WTLRRACFKI 
      1030       1040       1050       1060       1070       1080 
VEHNWFETFI VFMILLSSGA LAFEDIYIEQ RRVIRTILEY ADKVFTYIFI LEMLLKWVAY 
      1090       1100       1110       1120       1130       1140 
GFKVYFTNAW CWLDFLIVDV SIISLVANWL GYSELGPIKS LRTLRALRPL RALSRFEGMR 
      1150       1160       1170       1180       1190       1200 
VVVNALLGAI PSIMNVLLVC LIFWLIFSIM GVNLFAGKFY YCVNTTTSER FDISVVNNKS 
      1210       1220       1230       1240       1250       1260 
ESESLMYTGQ VRWMNVKVNY DNVGLGYLSL LQVATFKGWM DIMYAAVDSR EKEEQPHYEV 
      1270       1280       1290       1300       1310       1320 
NLYMYLYFVI FIIFGSFFTL NLFIGVIIDN FNQQKKKFGG KDIFMTEEQK KYYNAMKKLG 
      1330       1340       1350       1360       1370       1380 
SKKPQKPIPR PQNKIQGMVY DFVTKQVFDI SIMILICLNM VTMMVETDDQ SQLKVDILYN 
      1390       1400       1410       1420       1430       1440 
INMVFIIIFT GECVLKMFAL RHYYFTIGWN IFDFVVVILS IVGLALSDLI QKYFVSPTLF 
      1450       1460       1470       1480       1490       1500 
RVIRLARIGR VLRLIRGAKG IRTLLFALMM SLPALFNIGL LLFLVMFIYS IFGMSNFAYV 
      1510       1520       1530       1540       1550       1560 
KKESGIDDMF NFETFGNSII CLFEITTSAG WDGLLNPILN SGPPDCDPTL ENPGTNVRGD 
      1570       1580       1590       1600       1610       1620 
CGNPSIGICF FCSYIIISFL IVVNMYIAII LENFNVATEE SSEPLSEDDF EMFYETWEKF 
      1630       1640       1650       1660       1670       1680 
DPDATQFIDY SRLSDFVDTL QEPLKIAKPN KIKLITLDLP MVPGDKIHCL DILFALTKEV 
      1690       1700       1710       1720       1730       1740 
LGDSGEMDAL KQTMEEKFMA ANPSKVSYEP ITTTLKRKQE EVCAIKIQRA YRRHLLQRSV 
      1750       1760       1770       1780       1790       1800 
KQASYMYRHS QDGNDDGAPE KEGLLANTMN KMYGHEKEGD GVQSQGEEEK ASTEDAGPTV 
      1810       1820       1830       1840    
EPEPTSSSDT ALTPSPPPLP PSSSPPQGQT VRPGVKESLV 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P15390-1-unknown MASSSL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KESLV 1840 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)