TopFIND 4.0

P15428: 15-hydroxyprostaglandin dehydrogenase [NAD(+)]

General Information

Protein names
- 15-hydroxyprostaglandin dehydrogenase NAD(+)]
- 15-PGDH
- 1.1.1.141
- Prostaglandin dehydrogenase 1
- Short chain dehydrogenase/reductase family 36C member 1
Gene names HPGD
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P15428

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHVNGKVALV TGAAQGIGRA FAEALLLKGA KVALVDWNLE AGVQCKAALD EQFEPQKTLF 
        70         80         90        100        110        120 
IQCDVADQQQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EKTLQINLVS VISGTYLGLD 
       130        140        150        160        170        180 
YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIVG FTRSAALAAN LMNSGVRLNA 
       190        200        210        220        230        240 
ICPGFVNTAI LESIEKEENM GQYIEYKDHI KDMIKYYGIL DPPLIANGLI TLIEDDALNG 
       250        260    
AIMKITTSKG IHFQDYDTTP FQAKTQ

Isoforms

- Isoform 2 of 15-hydroxyprostaglandin dehydrogenase [NAD(+)] - Isoform 3 of 15-hydroxyprostaglandin dehydrogenase [NAD(+)] - Isoform 4 of 15-hydroxyprostaglandin dehydrogenase [NAD(+)] - Isoform 5 of 15-hydroxyprostaglandin dehydrogenase [NAD(+)]

Sequence View

        10         20         30         40         50         60 
MHVNGKVALV TGAAQGIGRA FAEALLLKGA KVALVDWNLE AGVQCKAALD EQFEPQKTLF 
        70         80         90        100        110        120 
IQCDVADQQQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EKTLQINLVS VISGTYLGLD 
       130        140        150        160        170        180 
YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIVG FTRSAALAAN LMNSGVRLNA 
       190        200        210        220        230        240 
ICPGFVNTAI LESIEKEENM GQYIEYKDHI KDMIKYYGIL DPPLIANGLI TLIEDDALNG 
       250        260    
AIMKITTSKG IHFQDYDTTP FQAKTQ         10         20         30         40         50         60 
MHVNGKVALV TGAAQGIGRA FAEALLLKGA KVALVDWNLE AGVQCKAALD EQFEPQKTLF 
        70         80         90        100        110        120 
IQCDVADQQQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EKTLQINLVS VISGTYLGLD 
       130        140        150        160        170        180 
YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIVG FTRSAALAAN LMNSGVRLNA 
       190        200        210        220        230        240 
ICPGFVNTAI LESIEKEENM GQYIEYKDHI KDMIKYYGIL DPPLIANGLI TLIEDDALNG 
       250        260    
AIMKITTSKG IHFQDYDTTP FQAKTQ         10         20         30         40         50         60 
MHVNGKVALV TGAAQGIGRA FAEALLLKGA KVALVDWNLE AGVQCKAALD EQFEPQKTLF 
        70         80         90        100        110        120 
IQCDVADQQQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EKTLQINLVS VISGTYLGLD 
       130        140        150        160        170        180 
YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIVG FTRSAALAAN LMNSGVRLNA 
       190        200        210        220        230        240 
ICPGFVNTAI LESIEKEENM GQYIEYKDHI KDMIKYYGIL DPPLIANGLI TLIEDDALNG 
       250        260    
AIMKITTSKG IHFQDYDTTP FQAKTQ         10         20         30         40         50         60 
MHVNGKVALV TGAAQGIGRA FAEALLLKGA KVALVDWNLE AGVQCKAALD EQFEPQKTLF 
        70         80         90        100        110        120 
IQCDVADQQQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EKTLQINLVS VISGTYLGLD 
       130        140        150        160        170        180 
YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIVG FTRSAALAAN LMNSGVRLNA 
       190        200        210        220        230        240 
ICPGFVNTAI LESIEKEENM GQYIEYKDHI KDMIKYYGIL DPPLIANGLI TLIEDDALNG 
       250        260    
AIMKITTSKG IHFQDYDTTP FQAKTQ



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)