TopFIND 4.0

P15586: N-acetylglucosamine-6-sulfatase

General Information

Protein names
- N-acetylglucosamine-6-sulfatase
- 3.1.6.14
- Glucosamine-6-sulfatase
- G6S
Gene names GNS
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P15586

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLLPLAPGR LRRGSPRHLP SCSPALLLLV LGGCLGVFGV AAGTRRPNVV LLLTDDQDEV 
        70         80         90        100        110        120 
LGGMTPLKKT KALIGEMGMT FSSAYVPSAL CCPSRASILT GKYPHNHHVV NNTLEGNCSS 
       130        140        150        160        170        180 
KSWQKIQEPN TFPAILRSMC GYQTFFAGKY LNEYGAPDAG GLEHVPLGWS YWYALEKNSK 
       190        200        210        220        230        240 
YYNYTLSING KARKHGENYS VDYLTDVLAN VSLDFLDYKS NFEPFFMMIA TPAPHSPWTA 
       250        260        270        280        290        300 
APQYQKAFQN VFAPRNKNFN IHGTNKHWLI RQAKTPMTNS SIQFLDNAFR KRWQTLLSVD 
       310        320        330        340        350        360 
DLVEKLVKRL EFTGELNNTY IFYTSDNGYH TGQFSLPIDK RQLYEFDIKV PLLVRGPGIK 
       370        380        390        400        410        420 
PNQTSKMLVA NIDLGPTILD IAGYDLNKTQ MDGMSLLPIL RGASNLTWRS DVLVEYQGEG 
       430        440        450        460        470        480 
RNVTDPTCPS LSPGVSQCFP DCVCEDAYNN TYACVRTMSA LWNLQYCEFD DQEVFVEVYN 
       490        500        510        520        530        540 
LTADPDQITN IAKTIDPELL GKMNYRLMML QSCSGPTCRT PGVFDPGYRF DPRLMFSNRG 
       550    
SVRTRRFSKH LL

Isoforms

- Isoform 2 of N-acetylglucosamine-6-sulfatase

Sequence View

        10         20         30         40         50         60 
MRLLPLAPGR LRRGSPRHLP SCSPALLLLV LGGCLGVFGV AAGTRRPNVV LLLTDDQDEV 
        70         80         90        100        110        120 
LGGMTPLKKT KALIGEMGMT FSSAYVPSAL CCPSRASILT GKYPHNHHVV NNTLEGNCSS 
       130        140        150        160        170        180 
KSWQKIQEPN TFPAILRSMC GYQTFFAGKY LNEYGAPDAG GLEHVPLGWS YWYALEKNSK 
       190        200        210        220        230        240 
YYNYTLSING KARKHGENYS VDYLTDVLAN VSLDFLDYKS NFEPFFMMIA TPAPHSPWTA 
       250        260        270        280        290        300 
APQYQKAFQN VFAPRNKNFN IHGTNKHWLI RQAKTPMTNS SIQFLDNAFR KRWQTLLSVD 
       310        320        330        340        350        360 
DLVEKLVKRL EFTGELNNTY IFYTSDNGYH TGQFSLPIDK RQLYEFDIKV PLLVRGPGIK 
       370        380        390        400        410        420 
PNQTSKMLVA NIDLGPTILD IAGYDLNKTQ MDGMSLLPIL RGASNLTWRS DVLVEYQGEG 
       430        440        450        460        470        480 
RNVTDPTCPS LSPGVSQCFP DCVCEDAYNN TYACVRTMSA LWNLQYCEFD DQEVFVEVYN 
       490        500        510        520        530        540 
LTADPDQITN IAKTIDPELL GKMNYRLMML QSCSGPTCRT PGVFDPGYRF DPRLMFSNRG 
       550    
SVRTRRFSKH LL



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)