P15884: Transcription factor 4

General Information

Protein names	- Transcription factor 4 - TCF-4 - Class B basic helix-loop-helix protein 19 - bHLHb19 - Immunoglobulin transcription factor 2 - ITF-2 - SL3-3 enhancer factor 2 - SEF-2
Gene names	TCF4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P15884

4 N-termini

20 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform SEF2-1A of Transcription factor 4 - Isoform SEF2-1D of Transcription factor 4 - Isoform B+delta of Transcription factor 4 - Isoform B-delta of Transcription factor 4 - Isoform A- of Transcription factor 4 - Isoform G- of Transcription factor 4 - Isoform H- of Transcription factor 4 - Isoform D- of Transcription factor 4 - Isoform F- of Transcription factor 4 - Isoform 11 of Transcription factor 4 - Isoform E- of Transcription factor 4 - Isoform 13 of Transcription factor 4 - Isoform C- of Transcription factor 4 - Isoform C-delta of Transcription factor 4 - Isoform I- of Transcription factor 4 - Isoform H- of Transcription factor 4

Sequence View

        10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM         10         20         30         40         50         60
MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG
        70         80         90        100        110        120
NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG
       130        140        150        160        170        180
CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL
       190        200        210        220        230        240
PSSVYAPSAS TADYNRDSPG YPSSKPATST FPSSFFMQDG HHSSDPWSSS SGMNQPGYAG
       250        260        270        280        290        300
MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPM STFHRSGTNH YSTSSCTPPA
       310        320        330        340        350        360
NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA
       370        380        390        400        410        420
VWSRNGGQAS SSPNYEGPLH SLQSRIEDRL ERLDDAIHVL RNHAVGPSTA MPGGHGDMHG
       430        440        450        460        470        480
IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVA LRGSHSLLPN QVPVPQLPVQ
       490        500        510        520        530        540
SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKD
       550        560        570        580        590        600
IKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP
       610        620        630        640        650        660
QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA

SNHMGQM

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 20 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P15884-1-unknown	MHHQQR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P15884-1-unknown	MHHQQR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78176
P15884-1-unknown	MHHQQR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78177
P15884-1-unknown	MHHQQR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78178
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455135
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000445202
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440731
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455346
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456983
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454584
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457113
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455163
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457747
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454328
P15884-25-unknown	MFSPPV...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454352
P15884-25-unknown	MFSPPV...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195351
P15884-25-unknown	MFSPPV...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195352
P15884-25-unknown	MFSPPV...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195353
P15884-80-unknown	MTSRDL...	80	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454866
P15884-80-unknown	MTSRDL...	80	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196644
P15884-80-unknown	MTSRDL...	80	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196645
P15884-80-unknown	MTSRDL...	80	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196646
P15884-131-unknown	MDMGNP...	131	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78182
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000439827
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455179
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454647
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455304
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455071
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458122
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456802
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457245
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468277
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456220
P15884-131-unknown	MDMGNP...	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456917
P15884-131-unknown	MDMGNP...	131	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101681
P15884-131-unknown	MDMGNP...	131	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101682
P15884-131-unknown	MDMGNP...	131	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101683

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SGKNGP	36	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454441
...SGKNGP	36	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153783
...SGKNGP	36	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153784
...SGKNGP	36	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153785
...HFTGSN	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457082
...HFTGSN	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153871
...HFTGSN	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153872
...HFTGSN	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153873
...QGCHQQ	123	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454352
...QGCHQQ	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154651
...QGCHQQ	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154652
...QGCHQQ	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154653
...QGCHQQ	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154654
...MDMGNP	135	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454866
...MDMGNP	135	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154791
...NPGTLS	139	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455450
...NPGTLS	139	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154844
...NPRRRP	159	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454328
...NPRRRP	159	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155100
...NPRRRP	159	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155101
...NPRRRP	159	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155102
...NPRRRP	159	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155103
...SAMEVQ	168	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457747
...SAMEVQ	168	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155237
...SAMEVQ	168	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155238
...SAMEVQ	168	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155239
...SAMEVQ	168	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155240
...MEVQTK	170	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456917
...MEVQTK	170	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155273
...MEVQTK	170	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155274
...MEVQTK	170	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155275
...MEVQTK	170	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155276
...VRKVPP	177	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455163
...VRKVPP	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155356
...VRKVPP	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155357
...VRKVPP	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155358
...VRKVPP	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155359
...PPGLPS	181	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457113
...PPGLPS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155404
...PPGLPS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155405
...PPGLPS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155406
...PPGLPS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155407
...GLPSSV	183	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468277
...GLPSSV	183	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456220
...GLPSSV	183	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155440
...GLPSSV	183	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155441
...GLPSSV	183	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155442
...GLPSSV	183	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155443
...SSSGMN	233	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454584
...YAGMLG	242	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457245
...NSSHIP	248	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456802
...SSHIPQ	249	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458122
...PQSSSY	253	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455071
...DINSSL	276	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457392
...RSGTNH	289	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456983
...TNHYST	292	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455304
...HMGQM	667	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73797
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73793
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73800
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73799
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73798
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73796
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73795
...HMGQM	667	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73794

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)