P16035: Metalloproteinase inhibitor 2

General Information

Protein names	- Metalloproteinase inhibitor 2 - CSC-21K - Tissue inhibitor of metalloproteinases 2 - TIMP-2
Gene names	TIMP2
Organism	Homo sapiens
Protease Family
Protease ID	I35.002
Chromosome location
UniProt ID	P16035

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGAAARTLRL ALGLLLLATL LRPADACSCS PVHPQQAFCN ADVVIRAKAV SEKEVDSGND
        70         80         90        100        110        120
IYGNPIKRIQ YEIKQIKMFK GPEKDIEFIY TAPSSAVCGV SLDVGGKKEY LIAGKAEGDG
       130        140        150        160        170        180
KMHITLCDFI VPWDTLSTTQ KKSLNHRYQM GCECKITRCP MIPCYISSPD ECLWMDWVTE
       190        200        210        220
KNINGHQAKF FACIKRSDGS CAWYRGAAPP KQEFLDIEDP

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P16035-27-unknown	CSCSPV...	27	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P16035-78-unknown	MFKGPE...	78	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467584
P16035-78-unknown	MFKGPE...	78	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000441724
P16035-78-unknown	MFKGPE...	78	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468296

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DIEDP	220	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)